Results 101 to 110 of about 123,459 (378)

Neutrophilic dermatosis of the dorsal hands: response to dapsone monotherapy [PDF]

Anais Brasileiros de Dermatologia, 2018
: Neutrophilic dermatosis of the dorsal hands is considered a rare and localized variant of Sweet's syndrome. Although the etiology is unknown, there are reports of association with infections, neoplasias, autoimmune diseases and medications ...
Felipe Siqueira Ramos, Flávia Regina Ferreira, Fátima Maria de Oliveira Rabay, Marcia Lanzoni de Alvarenga Lira   +3 more
doaj   +1 more source

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Genomic landscape of Neutrophilic Leukemias of Ambiguous Diagnosis.

Blood, 2019
Chronic neutrophilic leukemia (CNL), atypical chronic myeloid leukemia (aCML), and myelodysplastic/myeloproliferative neoplasms, unclassifiable (MDS/MPN-U) are a group of rare, heterogeneous myeloid disorders.
Haijiao Zhang, Beth Wilmot, D. Bottomly, K. Dao, Emily A. Stevens, C. Eide, V. Khanna, Angela Rofelty, S. Savage, Anna Reister-Schultz, Nicola Long, Libbey White, A. Carlos, Rachel Henson, Chen-Jzong Lin, R. Searles, R. Collins, D. DeAngelo, M. Deininger, Tamara J. Dunn, H. Than, M. Luskin, B. Medeiros, S. Oh, D. Pollyea, D. Steensma, R. Stone, B. Druker, S. McWeeney, Julia E. Maxson, J. Gotlib, J. Tyner   +31 more
semanticscholar   +1 more source

Alterations in serum amino acid concentrations in dogs with protein-losing enteropathy [PDF]

, 2018
BackgroundCertain amino acids are decreased in humans with inflammatory bowel disease (IBD) and supplementation with the same amino acids has shown beneficial effects in animal models of IBD.
Allenspach, Beeken, Bettenworth, Clayton, Coburn, Dąbrowski, Gupta, Hashimoto, Hou, Kim, Kim, Li, Liu, Liu, Middleton, Morgan, Nikolaus, Ren, Richard, Ruth, Schrocksnadel, Tsune, Walser, Wang, Widner, Xin   +25 more
core   +4 more sources

TimeFlow 2: An Unsupervised Cell Lineage Detection Method for Flow Cytometry Data

Cytometry Part A, EarlyView.
TimeFlow 2 is a new method for cell lineage inference in flow cytometry data. It constructs cell state paths along pseudotime and aggregates them into biologically informative groups. It allows tracking of cytometry markers within each automatically inferred lineage.
Margarita Liarou, Thomas Matthes, Stéphane Marchand‐Maillet   +2 more
wiley   +1 more source

Neutrophilic Dermatoses: A Case Series of Unusual Adverse Effects with Commonly Administered Drugs

Journal of Clinical and Diagnostic Research
Neutrophilic Dermatoses (NDs) are inflammatory conditions characterised by sterile neutrophilic infiltrates on histopathology. Multiple clinical presentations can occur in a single patient with ND. The location of the neutrophilic infiltrate (in the skin’
Yeragonda Susmitha, TS Rajashekar, K Suresh Kumar   +2 more
doaj   +1 more source

Prefixation of Neutrophils for Neutrophil Antibody Testing [PDF]

Laboratory Medicine, 2014
The granulocyte immunofluorescence test based on flow cytometry is still the most commonly used method for detecting antineutrophil antibodies. We questioned whether neutrophil prefixation is necessary for this test.Three pretreatment methods using paraformaldehyde were compared: unfixed, short-fixed (3 minutes 40 seconds), and long-fixed (10 minutes ...
Ye Jee, Shim, Dong Il, Won
openaire   +2 more sources

Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]

, 2019
Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H, Ge, Moyar Q, Haczku, Angela, Hwang, Jin W, Jiang, Zhilong, Kokalari, Blerina, Redai, Imre G   +6 more
core  

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Efficacy of Ruxolitinib in Patients With Chronic Neutrophilic Leukemia and Atypical Chronic Myeloid Leukemia.

Journal of Clinical Oncology, 2019
PURPOSE Colony-stimulating factor-3 receptor (CSF3R)-T618I is a recurrent activating mutation in chronic neutrophilic leukemia (CNL) and to a lesser extent in atypical chronic myeloid leukemia (aCML) resulting in constitutive JAK-STAT signaling.
K. Dao, J. Gotlib, Michael Deininger, S. Oh, J. Cortes, R. Collins, E. Winton, Dana R Parker, Hyunjung Lee, Anna Reister, Schultz, S. Savage, Stevens, Chase Brockett, N. Subbiah, R. Press, Philipp W. Raess, Michael J. Cascio, J. Dunlap, Yiyi Chen, C. Degnin, Julia E. Maxson, C. Tognon, T. Macey, B. Druker, J. Tyner   +25 more
semanticscholar   +1 more source