Results 121 to 130 of about 94,980 (286)
ResearchMetabolic dysfunction-associated steatohepatitis (MASH) is the progressive form of metabolic dysfunction-associated steatotic liver disease (MASLD), and closely associated with a high risk of liver-related morbidity and mortality.
Mengqi Fan +15 more
doaj +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Differentiation syndrome (DS) and Sweet syndrome (SS) are inflammatory complications mediated by cytokine dysregulation, classically associated with therapies that promote myeloid differentiation or cytokine release. While DS has been primarily linked to all‐trans retinoic acid (ATRA) and IDH inhibitors, recent evidence suggests that ...
Katerina Grafanaki +6 more
wiley +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang +5 more
wiley +1 more source
Frontiers in ImmunologyInterleukin-6 (IL-6) trans-signaling modulates immune responses in asthma, yet the mechanisms linking this pathway to Th17 skewing in neutrophilic asthma remain incompletely defined.
Suhua Zhu +7 more
doaj +1 more source
Neutrophil and neutrophil extracellular trap involvement in neutrophilic asthma: A review
MedicineAsthma is a highly prevalent chronic inflammatory disease characterized by variable airflow obstruction and airway hyperresponsiveness. Neutrophilic asthma (NA) is classified as “type 2 low” asthma, defined as 65% or more neutrophils in the total cell count.
Yuemu Li, Tianyi Yang, Baihua Jiang
openaire +2 more sources
A Rapidly Progressive Necrotic Ulcer in an Immunocompromised Patient
JEADV Clinical Practice, EarlyView.
R. Almutairi +5 more
wiley +1 more source
Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases
Prenatal Diagnosis, EarlyView.ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei +9 more
wiley +1 more source
Respirology, EarlyView.ABSTRACT Chronic obstructive pulmonary disease (COPD) remains the third leading cause of death worldwide, and conventional bronchodilator‐based therapies have limited efficacy in preventing exacerbations and disease progression. The 2024–2026 period represents a historic inflection point: three mechanistically distinct agents received Food and Drug ...
Naoya Fujino, Hisatoshi Sugiura
wiley +1 more source
Veterinary SciencesThis study aimed to evaluate differences in the production of reactive oxygen species (ROS) by peripheral blood neutrophils in healthy dogs, dogs with superficial pyoderma, and dogs with sterile neutrophilic dermatitis using the nitroblue tetrazolium ...
Marina García +4 more
doaj +1 more source