Results 151 to 160 of about 94,980 (286)
Navigating through uncertainty—Experience from the UK national VEXAS MDT
Summary The objective of this study was to describe the establishment, structure and influence of the United Kingdom national multidisciplinary team (MDT) for vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic (VEXAS) syndrome and to assess its clinical outputs and perceived value among participating clinicians.
Daniel Pietsch +51 more
wiley +1 more source
Summary Genomic technologies including next‐generation sequencing (NGS) and arrays for cytogenetic anomalies are now standard of care in England for the diagnostic evaluation of patients with suspected haematological malignancies. Challenges remain in the management of potential germline findings as a result of NGS panels and copy number variant ...
B. Speight +12 more
wiley +1 more source
TGF‐β Inhibitor Potentiates Osimertinib‐Induced Anti‐Tumor Immunity in Egfr‐Mutant Lung Cancer
Osimertinib enhances CD8+ T cell activity but also upregulates immunosuppressive TGF‐β in Egfr‐mutant lung tumors. This study demonstrates that TGF‐β inhibition with nintedanib or vactosertib potentiates osimertinib‐induced CD8+ T cell–mediated immunity and reduce CD206+ macrophages. These findings provide a strong rationale for novel immunotherapeutic
Tadahiro Kuribayashi +17 more
wiley +1 more source
Depletion of Neonatal Neutrophilic Cells Worsens the Outcome of E. coli Sepsis in Newborn Mice. [PDF]
Schwarz J +8 more
europepmc +1 more source
Unusual Abdominal Wall Complication After a Bilateral Transversus Abdominis Plane Block for Postoperative Analgesia. [PDF]
Pius A, Durgham B, Vanbeek S, Fye E.
europepmc +1 more source
Summary Background and Objectives: Diagnosing cicatricial alopecia is challenging. Even with histology, a definitive diagnosis cannot always be made. Line‐field confocal optical coherence tomography (LC‐OCT), a non‐invasive imaging method with high resolution used in vivo, has proven helpful in diagnosing scarring alopecia.
Marie‐Christine Nutz +5 more
wiley +1 more source
Bullous Rheumatoid Neutrophilic Dermatosis-A Systematic Review of 28 Cases. [PDF]
Mazur E +4 more
europepmc +1 more source
Aryl hydrocarbon receptor in club cells drives Th17-mediated lung injury following inhalation exposure to environmentally persistent free radicals. [PDF]
Pathak R +4 more
europepmc +1 more source

