Results 181 to 190 of about 94,980 (286)

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Rapidly progressing idiopathic neutrophilic vasculitis with fibrinoid necrosis of the central nervous system. [PDF]

BMJ Case Rep
Godsey L, Barbour CM, Leal SM, Benson PV, Milner D, Wick N, Lyerly M, Chkheidze R.   +7 more
europepmc   +1 more source

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

The FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin, Sumit Bhutada, Suneel S. Apte   +2 more
wiley   +1 more source

Fasudil improves neutrophilic asthma by influencing M1 macrophage polarization and the expression of the NF-κB/TLR-2/RPS3 pathway. [PDF]

Am J Transl Res
Guo SD, Liu CY, Liu R, Zhang YP, Zuo LY, Cui CY, Cheng J, Lin T.   +7 more
europepmc   +1 more source

Giant cellulitis‐like Sweet's syndrome induced by gilteritinib

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Juan de Luque‐Fernández, Irene Rivera‐Ruiz, Irene Suárez‐Vergne, Inmaculada Sánchez‐Ramírez, Manuel Galán‐Gutiérrez, Antonio José Vélez García‐Nieto   +5 more
wiley   +1 more source

Chronic ulcerative oesophagitis rich in IgG4‐positive plasma cells – a distinct clinicopathological entity

Histopathology, EarlyView.
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger, Ian Brown, Anthony J Gill, Tomas Slavik, Giuseppe Zamboni, Cord Langner   +5 more
wiley   +1 more source

The convergent pathway of obstructive lung disease: the disease-modifying potential of dipeptidyl peptidase 1 inhibition in COPD, asthma and bronchiectasis overlap. [PDF]

Drugs Context
Menzella F, Cottini M, Lombardi C, Chan R.   +3 more
europepmc   +1 more source

Calcification and tumour‐infiltrating lymphocytes predict upgrade of human epidermal growth factor 2 (HER2)‐negative ductal carcinoma in situ diagnosed on core needle biopsy

Histopathology, EarlyView.
With evolving paradigm in treatment of patient diagnosed with pure ductal carcinoma in situ (DCIS), it is essential to stratify patients at low risk for upgrade to invasive disease at subsequent excision to inform management decisions. When combined with adequate sampling and intrinsic tumour characteristics, tumour microenvironment (TME) features ...
Monalyn Marabi, Yuyang Li, Chaiwat Aphivatanasiri, Julia Y Tsang, Joshua JX Li, Lin‐Ying Chen, Gary M Tse   +6 more
wiley   +1 more source

Postoperative Pyoderma Gangrenosum: Rare Infection Mimic and Diagnostic Challenge - A Case Report. [PDF]

Visc Med
Aldarwish S, Schafmayer C, Hinz S.
europepmc   +1 more source

Aseptic meningitis due to intravenous immunoglobulin therapy (IVIG) in therapy‐refractory pyoderma gangraenosum

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Katharina A. Kälber, Knut Schäkel, Alexander Enk, Julia K. Winkler   +3 more
wiley   +1 more source