Results 191 to 200 of about 94,980 (286)

Mucous Membrane Pemphigoid After Anti‐PD‐1 Therapy: Risk‐Stratified Management and Treatment Outcomes

International Journal of Dermatology, EarlyView.
ABSTRACT Mucous membrane pemphigoid (MMP) following anti‐programmed cell death‐1 (PD‐1) therapy is rare but increasingly reported. Management of high‐ and low‐risk MMP in this setting and the potential oncologic trade‐offs remain poorly defined. We performed a narrative synthesis of all published cases of anti‐PD‐1‐associated MMP, following MEDLINE ...
Serena Dienes, Negar Esfandiari, Steven Daveluy   +2 more
wiley   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, EarlyView.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Noninfectious Necrotizing Aortitis With Predominantly Neutrophilic Infiltrate. [PDF]

Case Rep Pathol
Williams NA, Colantonio M, Miller A, Burke AP.   +3 more
europepmc   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini, Gioele Gioco, Michele Davide Mignogna, Stefania Leuci, Francesco Scilla, Davide Gentile, Cosimo Rupe, Enrico Russo, Anna Schiavelli, Carlo Lajolo   +9 more
wiley   +1 more source

Interleukin-23 in lung and airway diseases: from pathogenesis to precision-guided therapeutic targeting. [PDF]

Front Pharmacol
Nayak BB, Rajesh R, Teppan J, Gogg T, Böhm E.   +4 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Nociceptor neurons control pollution-mediated neutrophilic asthma. [PDF]

Elife
Wang JC, Kulle A, Crosson T, Reza Nikpoor A, Gupta S, Roger A, Rafei M, Thanabalasuriar A, Talbot S.   +8 more
europepmc   +1 more source

Canine chronic idiopathic rhinitis: management and outcome – a single‐centre retrospective observational study

Journal of Small Animal Practice, EarlyView.
Objectives Canine chronic idiopathic rhinitis is a common cause of nasal disease in dogs but data reporting outcomes following treatment is lacking. The aim was to describe pre‐ and post‐referral management and outcomes of dogs diagnosed with canine chronic idiopathic rhinitis at a single referral centre.
P. M. N. Henry, R. Rizzo, Y. Tan, A. M. Boag, J. Del‐Pozo, G. A. Woods   +5 more
wiley   +1 more source

The Evolving Landscape of COPD Typization. [PDF]

Medicina (Kaunas)
Fantin A, Castaldo N, Sartori G, di Chiara C, Patrucco F, Morana G, Patruno V, Crisafulli E.   +7 more
europepmc   +1 more source

From Culture to Sequencing: Evolving Strategies for the Diagnosis of Pediatric Spondylodiscitis

Orthopaedic Surgery, EarlyView.
Diagnostic approaches to pediatric spondylodiscitis have evolved from culture‐based methods with limited sensitivity to advanced molecular and sequencing technologies. Metagenomic next‐generation sequencing (mNGS) enables rapid, culture‐independent pathogen identification, improving diagnostic accuracy, guiding therapy, and reducing invasive procedures
Viola Sbampato, Ahmer Ahmad Khan, Andreas Tsoupras, Giacomo De Marco, Dimitri Ceroni   +4 more
wiley   +1 more source