Results 201 to 210 of about 94,980 (286)

TNF Inhibitor Therapy in Corticosteroid‐Resistant or ‐Dependent Pediatric Neutrophilic Dermatosis

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Neutrophilic dermatoses are rare in children. Systemic corticosteroids are the first‐line treatment, but guidelines for second‐line therapies are lacking. We report five cases of children with systemic steroid‐resistant/dependent neutrophilic dermatoses, successfully treated with tumor necrosis factor inhibitors.
Laure Chêne   +7 more
wiley   +1 more source

NEMO‐NDAS: Case Report and Review of the Literature

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT NEMO‐deleted exon 5 autoinflammatory syndrome (NEMO‐NDAS) is the result of a gain‐of‐function IKBKG pathogenic variant leading to dysregulated NF‐κB signaling and systemic inflammation. We present a case of NEMO‐NDAS in a 2‐year‐old female presenting with recurrent fevers, subcutaneous nodules, lymphadenopathy, and splenomegaly.
Angela Yang   +5 more
wiley   +1 more source

Effect of remobinant granulocyte-macrophage colony stimulating factor (GM-CSF) on leukopenia in AIDS [PDF]

open access: yes, 1991
Bogner, Johannes R.   +7 more
core  

Design and rationale of the AIR-NET trial: a randomised, open-label, multifactorial, multicentre, adaptive platform trial using a range of repurposed anti-inflammatory treatments to improve outcomes in patients with bronchiectasis within the EMBARC clinical research network. [PDF]

open access: yesERJ Open Res
Long MB   +20 more
europepmc   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva   +2 more
wiley   +1 more source

Biological definition of periodontal diseases: A historical review of host‐response diagnostics and their implications for disease classification

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Understanding periodontal diseases through a biological lens has been a central aim in periodontal research. Visionary pioneers in the field established the foundations of our knowledge, providing invaluable insights into disease mechanisms and progression.
Nagihan Bostanci   +2 more
wiley   +1 more source

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