Results 231 to 240 of about 123,459 (378)

Engineering Chimeric Hypoallergens for Safer and More Effective House Dust Mite Allergy Vaccines

Clinical &Experimental Allergy, EarlyView.
Eduardo S. da Silva, Antônio M. S. Fernandes, Elisânia F. Silveira, Raphael C. Silva, Leonardo F. Santiago, Luis F. S. Garcés, Sara Huber, Sabrina Wildner, Tafarel A. Souza, Vitor S. Alves, Lorena M. de Souza, Deise S. Vilas‐Bôas, Peter Briza, Peter Lackner, Luis G. C. Pacheco, Neuza M. Alcântara‐Neves, Fatima Ferreira, Carina S. Pinheiro   +17 more
wiley   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

S100A4 Induces Neutrophilic Inflammation in Chronic Rhinosinusitis with Nasal Polyps via TLR4 Pathway. [PDF]

J Clin Immunol
Tu Y, Li C, Li T, Liu J, Meng L, Liu S, Li P, Wan Y, Chen A, Shi L, Wang DY.   +10 more
europepmc   +1 more source

Teleost‐specific ictacalcins exhibit similar structural organization, cation‐dependent activation, and transcriptional regulation as human S100 proteins

The FEBS Journal, EarlyView.
Calcium‐binding S100 proteins are important mediators of inflammation in humans. Distant members of this family have been recently discovered in teleost fish but their resemblance to human proteins has not been explored yet. This study demonstrates that zebrafish‐specific S100i1 and S100i2 (ictacalcins) possess identical structural organization and ...
Liz Hernández, Théo Paris, Maria Demou, Catherine Birck, Christina Begon‐Pescia, Juan Francisco Rodríguez Vidal, Sylwia D. Tyrkalska, Charlotte Bureau, Catherine Gonzalez, Juliette Gracia, Etienne Lelièvre, Victoriano Mulero, Mai Nguyen‐Chi, Laure Yatime   +13 more
wiley   +1 more source

Rapid cutaneous remission response to tofacitinib and systemic corticosteroids in VEXAS syndrome with a novel UBA1 mutation. [PDF]

JAAD Case Rep
Wang Z, Shi H, Jiang Y.
europepmc   +1 more source

Illuminating neutrophilic myeloid neoplasms [PDF]

, 2019
Robert P. Hasserjian
openalex   +1 more source

Biomolecular Changes Upon Ablative Laser Therapy of the Skin: A Scoping Review

International Journal of Dermatology, EarlyView.
(Fractional) ablative laser therapy results in a wound healing response characterized by an inflammatory phase, dermal matrix degradation, and remodeling, collagenesis and elastogenesis. This is characterized by an increase in metalloproteinases, collagen type I, III, VII, and tropoelastin.
Marie‐Eline Pauline Henriette Debeuf, Maartje Hendrika Pieternel Rauwenhoff, Michel van Geel, Peter Martin Steijlen, Valerie Lydie Roland Marc Verstraeten   +4 more
wiley   +1 more source

Neutrophilic Asthma-From Mechanisms to New Perspectives of Therapy. [PDF]

J Clin Med
Iwaszko I, Specjalski K, Chełmińska M, Niedoszytko M.   +3 more
europepmc   +1 more source

Dysbiosis‐Mediated Inflammation: A Pathophysiological Link Between Rheumatoid Arthritis and Periodontitis

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To explore mechanistic links between rheumatoid arthritis (RA) and periodontitis (PD) through the lens of subgingival microbial dysbiosis–mediated inflammation. Methods Subgingival plaque from 100 volunteers with RA and PD (RAPD), 22 with RA (RAnoPD), 18 with PD (PDnoRA) and 19 healthy controls (noRAnoPD) was analysed using 16S‐amplicon ...
Isabel Lopez‐Oliva, Iain L. Chapple, Akshay Paropkari, Shweta Saraswat, Praveen Sharma, Stefan Serban, Paola de Pablo, Karim Raza, Andrew Filer, Thomas Dietrich, Melissa Grant, Purnima S. Kumar   +11 more
wiley   +1 more source

A tissue-penetrably engineered deoxyribonuclease 1 to prevent nasal polyp formation in chronic rhinosinusitis. [PDF]

BMC Pharmacol Toxicol
Kwak SB, Khalmuratova R, Kim SJ, Shin HW, Park JW.   +4 more
europepmc   +1 more source