Results 31 to 40 of about 123,459 (378)

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis [PDF]

open access: yes, 2010
Background: Acute generalized exanthematous pustulosis (AGEP) represents a severe, acute, pustular skin reaction that is most often induced by drugs. AGEP can be difficult to differentiate from generalized pustular psoriasis (GPP) both clinically and ...
Austin   +34 more
core   +3 more sources

Four-Parameter white blood cell differential counting based on light scattering measurements [PDF]

open access: yes, 1988
Measurement of the depolarized orthogonal light scattering in flow cytometry enables one to discriminate human eosinephilic granulocytes from neutrophilic granulocytes. We use this method to perform a four-parameter differential white blood cell analysis.
Greve, J.   +4 more
core   +2 more sources

Study on the Mutation Sites of CSF3R Responsible for the Clonal Advantage of Chronic Neutrophilic Leukemia

open access: yesCentral Asian Journal of Medical Sciences, 2016
Objectives: Chronic neutrophilic leukemia (CNL) is a rare, but distinct, entity within myeloproliferative neoplasms, characterized by splenomegaly, sustained mature neutrophilia, and absence of the Philadelphia chromosome. In 2013, oncogenic mutations in
Otgonbat Altangerel   +2 more
doaj   +1 more source

Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection [PDF]

open access: yes, 2015
Bioactive matrix fragments (matrikines) have been identified in a myriad of disorders, but their impact on the evolution of airway inflammation has not been demonstrated.
Snelgrove, RJ
core   +1 more source

Expansion of Thaumarchaeota habitat range is correlated with horizontal transfer of ATPase operons. [PDF]

open access: yes, 2019
Thaumarchaeota are responsible for a significant fraction of ammonia oxidation in the oceans and in soils that range from alkaline to acidic. However, the adaptive mechanisms underpinning their habitat expansion remain poorly understood.
Bartlett, Douglas H   +24 more
core   +2 more sources

Characterizing the Neutrophilic Inflammation in Chronic Rhinosinusitis With Nasal Polyps

open access: yesFrontiers in Cell and Developmental Biology, 2021
The mechanisms underlying neutrophilic inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP) remain poorly investigated. This study aimed to examine the factors that contribute to tissue neutrophilia in CRSwNP.
J. Ruan   +11 more
semanticscholar   +1 more source

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]

open access: yes, 2018
BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.

core   +2 more sources

Randomized preclinical study of machine perfusion in vascularized composite allografts

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin   +7 more
wiley   +1 more source

Isolation of phyllosilicate-iron redox cycling microorganisms from an illite-smectite rich hydromorphic soil

open access: yesFrontiers in Microbiology, 2012
The biogeochemistry of phyllosilicate-Fe redox cycling was studied in a Phalaris arundinacea (Reed Canary Grass) dominated redoximorphic soil from Shovelers Sink, a small glacial depression near Madison, WI.
Evgenya S Shelobolina   +7 more
doaj   +1 more source

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