Results 31 to 40 of about 95,721 (328)
The Role of Neutrophils and Neutrophil Elastase in Pneumococcal Pneumonia [PDF]
Frontiers in Cellular and Infection Microbiology, 2021 Streptococcus pneumoniae, also known as pneumococcus, is a Gram-positive diplococcus and a major human pathogen. This bacterium is a leading cause of bacterial pneumonia, otitis media, meningitis, and septicemia, and is a major cause of morbidity and mortality worldwide. To date, studies onS.
Hisanori Domon +3 more
openaire +4 more sources
Central Asian Journal of Medical Sciences, 2016 Objectives: Chronic neutrophilic leukemia (CNL) is a rare, but distinct, entity within myeloproliferative neoplasms, characterized by splenomegaly, sustained mature neutrophilia, and absence of the Philadelphia chromosome. In 2013, oncogenic mutations in
Otgonbat Altangerel +2 more
doaj +1 more source
Expansion of Thaumarchaeota habitat range is correlated with horizontal transfer of ATPase operons. [PDF]
, 2019 Thaumarchaeota are responsible for a significant fraction of ammonia oxidation in the oceans and in soils that range from alkaline to acidic. However, the adaptive mechanisms underpinning their habitat expansion remain poorly understood.
Bartlett, Douglas H +24 more
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Cell Cycle, 2015 Neutrophils are short-lived effector cells of the innate immune system that form the first line of defense against microbial pathogens.1 Recent studies show that, by migrating to bone marrow, these cells can also induce (VACV)-specific T cell responses.2 Neutrophils polarize to distinct phenotypes in response to environmental cytokine/chemokine signals.
Mariano Esteban, Mauro Di Pilato
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Mechanisms of Bacterial Extracellular Electron Exchange. [PDF]
, 2016 The biochemical mechanisms by which microbes interact with extracellular soluble metal ions and insoluble redox-active minerals have been the focus of intense research over the last three decades. The process presents two challenges to the microorganism;
Butt, Julea N. +5 more
core +1 more source
Biomedicines, 2023 Aim. To study the processes of lipid peroxidation and the activity of antioxidant defense enzymes depending on the chemiluminescent activity of neutrophilic granulocytes in patients with gastric cancer associated with H.
Olga Valentinovna Smirnova +2 more
doaj +1 more source
Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]
, 2018 BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.
core +2 more sources
Frontiers in Immunology, 2018 Neutrophils are abundant in the circulation and are one of the immune system's first lines of defense against infection. There has been substantial work carried out investigating the role of neutrophils in malaria and it is clear that during infection neutrophils are activated and are capable of clearing malaria parasites by a number of mechanisms ...
Aitken, EH, Alemu, A, Rogerson, SJ
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Circulation Research, 2015 More than a century ago, in 1881, Bizzozero1 discovered platelets and their role in primary hemostasis. Since this founding study, it has been shown that, in addition to the scaffold of platelets and fibrin, other proteins and cells play an important role in thrombus formation and stabilization.
Benoît Ho-Tin-Noé +1 more
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Airway monocyte modulation relates to tumour necrosis factor dysregulation in neutrophilic asthma
ERJ Open Research, 2021 Background Dysregulation of tumour necrosis factor-α (TNF-α) signalling is implicated in neutrophilic asthma. TNF-α signalling involves membrane-bound and soluble ligand (TNF-α) and receptors (TNFRs); however, little is known about how these proteins are
Natalie M. Niessen +5 more
doaj +1 more source