Results 71 to 80 of about 94,980 (286)

Alterations in serum amino acid concentrations in dogs with protein-losing enteropathy [PDF]

, 2018
BackgroundCertain amino acids are decreased in humans with inflammatory bowel disease (IBD) and supplementation with the same amino acids has shown beneficial effects in animal models of IBD.
Allenspach, Beeken, Bettenworth, Clayton, Coburn, Dąbrowski, Gupta, Hashimoto, Hou, Kim, Kim, Li, Liu, Liu, Middleton, Morgan, Nikolaus, Ren, Richard, Ruth, Schrocksnadel, Tsune, Walser, Wang, Widner, Xin   +25 more
core   +4 more sources

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Adenosine Triphosphate Promotes Allergen-Induced Airway Inflammation and Th17 Cell Polarization in Neutrophilic Asthma

Journal of Immunology Research, 2017
Adenosine triphosphate (ATP) is a key mediator to alert the immune dysfunction by acting on P2 receptors. Here, we found that allergen challenge caused an increase of ATP secretion in a murine model of neutrophilic asthma, which correlated well with ...
Fang Zhang, Xin Su, Gang Huang, Xiao-Feng Xin, E-Hong Cao, Yi Shi, Yong Song   +6 more
doaj   +1 more source

Neutrophilic Dermatoses: A Case Series of Unusual Adverse Effects with Commonly Administered Drugs

Journal of Clinical and Diagnostic Research
Neutrophilic Dermatoses (NDs) are inflammatory conditions characterised by sterile neutrophilic infiltrates on histopathology. Multiple clinical presentations can occur in a single patient with ND. The location of the neutrophilic infiltrate (in the skin’
Yeragonda Susmitha, TS Rajashekar, K Suresh Kumar   +2 more
doaj   +1 more source

Sweet’s Syndrome Arising in a Scar

Case Reports in Dermatology, 2017
Acute febrile neutrophilic dermatosis (Sweet’s syndrome) is an uncommon inflammatory cutaneous disorder. It presents with lesions which are tender, erythematous, edematous papules and under histologic examination show dense neutrophilic infiltration of ...
Casey M. Chern, Michael Royer, Winston Turnage   +2 more
doaj   +1 more source

Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]

, 2019
Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H, Ge, Moyar Q, Haczku, Angela, Hwang, Jin W, Jiang, Zhilong, Kokalari, Blerina, Redai, Imre G   +6 more
core  

β2-adrenergic agonists modulate TNF-α induced astrocytic inflammatory gene expression and brain inflammatory cell populations [PDF]

, 2014
Background: The NF-kappa B signaling pathway orchestrates many of the intricate aspects of neuroinflammation. Astrocytic beta(2)-adrenergic receptors have emerged as potential regulators in central nervous system inflammation and are potential targets ...
Aerts, Joeri L, De Keyser, Jacques, Demol, Frauke, Gerlo, Sarah, Laureys, Guy, Spooren, Anneleen   +5 more
core   +3 more sources

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Nitrate-Dependent Iron Oxidation: A Potential Mars Metabolism [PDF]

, 2018
This work considers the hypothetical viability of microbial nitrate-dependent Fe2+ oxidation (NDFO) for supporting simple life in the context of the early Mars environment.
Abramov, Amils, Anand, Arevalo, Arnold, Arvidson, Bauermeister, Benz, Bibring, Bridges, Bridges, Bruce, Busigny, Byrne-Bailey, Cabrol, Canfield, Carlson, Carlson, Carr, Chakraborty, Chakraborty, Changela, Charlou, Chassefière, Chastain, Chaudhuri, Chevrier, Cockell, Cockell, Cockell, Comeau, Czaja, Dartnell, Edwards, Edwards, Edwards, Ehlmann, Ehlmann, Ehlmann, Ehrenreich, Emerson, Emerson, Emerson, Etique, Ettwig, Fassett, Filiberto, Fisk, Formisano, Fowler, Fox, Fox, Fox-Powell, Frydenvang, Gauger, Gendrin, Glavin, Grady, Gronstal, Grotzinger, Grotzinger, Hafenbradl, Hecht, Hedrich, Hicks, Hoefen, Hoehler, Hoppert, Hurowitz, Ilbert, Ionescu, Irwin, Jakosky, Jepsen, Johnson, Kappler, Kappler, Kappler, King, Kish, Klueglein, Klueglein, Konhauser, Konn, Kounaves, Kumaraswamy, Lack, Lalonde, Lanza, Laufer, Lopez-Reyes, Lovley, Lovley, Madigan, Mahaffy, Malin, Mangold, Manning, Martin, Martín-Torres, Marzo, McSween, McSween, Michalski, Millero, Ming, Ming, Miot, Miot, Miot, Miot, Miot, Miot, Miot, Miot, Mirvaux, Montoya, Morgan, Morris, Morris, Morris, Muehe, Myers, Nachon, Navarro-González, Nealson, Nie, Nixon, Nixon, Nixon, Oren, Osinski, Palucis, Pantke, Parnell, Pirajno, Popa, Raghoebarsing, Raiswell, Ramirez, Rampe, Rampe, Reimers, Revsbech, Roden, Santelli, Schieber, Schuerger, Schwenzer, Schwenzer, Schädler, Sephton, Sholes, Smith, Smith, Squyres, Squyres, Squyres, Steele, Stern, Stern, Stevens, Straub, Straub, Straub, Strohm, Summers, Summers, Summers, Sutter, Toporski, Tosca, Tosca, Tuff, Vaniman, Visscher, Wacey, Weber, Weber, Weber, Webster, Welhan, Wheat, Williams, Yen, Yen   +185 more
core   +4 more sources

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source