The classical model of hematopoiesis predicts a dichotomous lineage restriction of multipotent hematopoietic progenitors (MPPs) into common lymphoid progenitors (CLPs) and common myeloid progenitors (CMPs).
André Görgens +6 more
doaj +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
The research has shown that the functional state of neutrophilic granulocytes (NG) is determined by the state of NG subpopulation phenotype composition in evaluating the simultaneous expression of CD16, CD32, CD11b membrane markers with considering the ...
G A Chudilova +4 more
doaj +1 more source
Neutrophilic granulocytes reactive response in candida vulvovaginitis patients with intracellular microorganism persistence complications [PDF]
: Polymorphic neutrophilic granulocytes reactive response and body immune reactivity in general considerably decrease in patients suffering from candida vaginitis on the basis of intracellular microorganisms ...
Djuiriak, V.S., Yakovychuk, N.D.,
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Orthopedic surgery increases atherosclerotic lesions and necrotic core area in ApoE-/- mice [PDF]
Background and aims Observational studies show a peak incidence of cardiovascular events after major surgery. For example, the risk of myocardial infarction increases 25-fold early after hip replacement.
Chen +39 more
core +2 more sources
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Chromatin swelling drives neutrophil extracellular trap release
Neutrophilic granulocytes release their own DNA (NETosis) as neutrophil extracellular traps to capture pathogens. Here, the authors use time-resolved fluorescence and atomic force microscopy and reveal that NETosis is highly organized into three distinct
Elsa Neubert +11 more
doaj +1 more source
The influence of surface morphology and wettability on the inflammatory response against poly(L-lactic acid): A semi-quantitative study with monoclonal antibodies [PDF]
In this study, the influence of surface morphology and wettability of both degradable and nondegradable polymer films on the inflammatory response after subcutaneous implantation in the rat was investigated.
Baier +46 more
core +3 more sources
Abstract Background Mucus parameters are hallmark diagnostic features of equine asthma (EA). Objectives To investigate the relationship between mucus quantity score and mucus viscosity score with signalment, history, clinical findings and cytological parameters. Study Design Retrospective cross‐sectional study.
Julia Drespling +5 more
wiley +1 more source
Cytological examination and cellular composition of bone marrow in healthy, adult, cynomolgus monkeys ( Macaca fascicularis ) [PDF]
The purpose of this study was to evaluate the cellular composition of the bone marrow of cynomolgus monkeys (Macaca fascicularis). Femoral bone marrow smears from 23 healthy, adult animals (11 males and 12 females) were examined.
Bolliger, A., Fontaine, M.
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