Results 201 to 210 of about 464,806 (262)

The role of neutrophils, fibroblasts, and osteoclasts in periodontitis: A transcriptomic and single-cell analysis. [PDF]

Medicine (Baltimore)
Xu Z, He Z, Yin C, Liu Q.
europepmc   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang, Tianzhen Hua, Meiling Wang, Bingbing Meng, Yue Zhang, Chengxu Jiang, Yunhe Gao, Hongqi Yang, Jian Bo   +8 more
wiley   +1 more source

Neutrophils and Neutrophil Extracellular Traps in Hepatic Ischemia-Reperfusion Injury: Molecular Mechanisms and Therapeutic Strategies. [PDF]

Int J Mol Sci
Xu F, Wang M, Wang B, Yang J, Qian X.
europepmc   +1 more source

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source

CD56⁺/CD38⁺ Neutrophils: Rapid and Specific Flow Cytometric Signature for Chronic Myeloid Leukemia. [PDF]

Mediterr J Hematol Infect Dis
Laganà A, Breccia M, Elia L, Scalzulli E, Bisegna ML, Ielo C, Buffolino S, Di Lascio A, Germano CA, Intoppa S, Milani ML, Martelli M, Breccia M, De Propris MS.   +13 more
europepmc   +1 more source

Characteristics of peripheral blood neutrophil subsets in patients with primary Sjogren's syndrome based on single-cell RNA sequencing. [PDF]

Front Immunol
Gao Z, Zheng J, Ma X, Han Y, Wang J, Fang L, Zhu H, Zhang X.   +7 more
europepmc   +1 more source

Neutrophil dysmorphisms and extracellular trap-like structures in a patient with severe coronavirus disease 2019. [PDF]

Rev Soc Bras Med Trop
Cucinelli ADES, Santos DRD, Kang HC, Pereira IR.   +3 more
europepmc   +1 more source

The Role of NADPH Oxidase 4 in Neutrophil-Mediated Immune Escape in Gastric Cancer. [PDF]

Int J Biol Sci
Jiang J, Xi W, Zheng Y, Ji J, Zhou C, Shi M, Wu J, Jin Y, Zhang B, Zhao L, Cai Q, Zhang J.   +11 more
europepmc   +1 more source

Thromboembolic ischemic stroke induces neutrophil recruitment and matrix metalloproteinase-9 release to enhance ischemic brain injury. [PDF]

Res Pract Thromb Haemost
Singh S, Houng A, Reed GL.
europepmc   +1 more source