Results 11 to 20 of about 1,573 (165)

Efficacy and Safety of Sonidegib in Adult Patients with Nevoid Basal Cell Carcinoma Syndrome (Gorlin Syndrome): Results from a Phase 2, Double-Blind, Randomized Trial [PDF]

Clinical, Cosmetic and Investigational Dermatology, 2020
John T Lear,1 Axel Hauschild,2 Eggert Stockfleth,3 Nicholas Squittieri,4 Nicole Basset-Seguin,5 Reinhard Dummer6 1Manchester Royal Infirmary, Manchester, UK; 2Klinik Für Dermatologie, Venerologie Und Allergologie Universitätsklinikum Schleswig ...
Lear JT, Hauschild A, Stockfleth E, Squittieri N, Basset-Seguin N, Dummer R   +5 more
doaj   +2 more sources

Genetic Insight into Gorlin–Goltz Syndrome

Indian Journal of Dermatology
Gorlin-Goltz syndrome, also called Basal cell nevus syndrome (BCNS), Nevoid basal cell carcinoma syndrome (NBCCS), or Basal nevus cell carcinoma syndrome (BNCCS) is a rare, inherited, autosomal dominant genodermatoses, with variable expression and ...
M Madhu
doaj   +2 more sources

Nevoid Basal Cell Carcinoma Syndrome

Dermatologic Clinics, 1987
Nevoid basal cell carcinoma syndrome has as its hallmarks such diverse manifestations as numerous cutaneous basal cell cancers and epidermal cysts, palmar and plantar pits, keratocysts of the jaw, calcified dural folds, various skeletal anomalies, cleft lip and/or palate, and various other neoplasms or hamartomas. Inheritance is autosomal dominant. The
Melanie D. Pratt, Robert Jackson
  +6 more sources

Nevoid Basal Cell Carcinoma Syndrome: A Long-Term Study in a Family. [PDF]

Craniomaxillofac Trauma Reconstr, 2016
de Santana Santos T, Vajgel A, Martins-Filho PR, de Albuquerque Maranhao Filho AW, De Holanda Vasconcellos RJ, Frota R, Filho JR.   +6 more
europepmc   +2 more sources

Gorlin syndrome presenting with a unilateral ovarian fibroma in a 22-year-old woman: a case report

Journal of Medical Case Reports, 2012
Introduction Nevoid basal cell carcinoma syndrome, or Gorlin syndrome, is an inherited disorder characterized by malignancies of the skin and other organs, skeletal abnormalities, and congenital malformations.
Finch Terence, Pushpanathan Chitra, Brown Krista, El-Gohary Yasser   +3 more
doaj   +1 more source

Nevoid Basal Cell Carcinoma Syndrome

Journal of Investigative Dermatology, 1994
The nevoid basal cell carcinoma syndrome is an autosomal dominant disorder that predisposes to basal cell carcinomas of the skin, ovarian fibromas, and medulloblastomas. Unlike other hereditary disorders associated with cancer, it features widespread developmental defects.
Bale, Allen E, Gailani, Mae R, Leffell, David J   +2 more
openaire   +2 more sources

Nevoid basal-cell carcinoma syndrome

Dermatology Online Journal, 2011
Gorlin syndrome is an autosomal dominantly inherited disorder that results in numerous basal cell carcinomas as well as a number of other facial and skeletal findings. We present a patient with many classic features and review some of the treatment options available for these patients.
Leger, Marie, Quintana, Adelle, Tzu, Julia, Yee, Herman, Kamino, Hideko, Sanchez, Miguel   +5 more
openaire   +5 more sources

Nevoid Basal Cell Carcinoma Syndrome: Report from the Zurich Nevoid Basal Cell Carcinoma Syndrome Cohort [PDF]

Dermatology, 2016
<b><i>Background:</i></b> Nevoid basal cell carcinoma syndrome (NBCCS, Gorlin-Goltz syndrome) presents various symptoms and can disfigure patients. The estimated prevalence is around 1:100,000. <b><i>Objective:</i></b> To systematically investigate the clinical manifestations of NBCCS patients of the ...
Rehefeldt-Erne, Susanne, Nägeli, Mirjam C, Winterton, Nina, Felderer, Lea, Weibel, Lisa, Hafner, Jürg, Dummer, Reinhard   +6 more
openaire   +4 more sources

A novel PTCH1 germline mutation distinguishes basal cell carcinoma from basaloid follicular hamartoma: a case report

Journal of Medical Case Reports, 2009
Introduction Nevoid basal cell carcinoma syndrome is a rare autosomal dominant disorder characterized by numerous basal cell carcinomas, odontogenic keratocysts of the jaws and developmental defects. The disorder results from mutations in the PTCH1 gene.
Hellani Ali, Baghdadi Hiba, Dabbour Nidal, Almassri Nidal, Abu-Amero Khaled K   +4 more
doaj   +1 more source

Gorlin-Goltz syndrome: A rare case

Indian Journal of Dermatology, 2015
Gorlin-Goltz syndrome or nevoid basal cell carcinoma syndrome is characterized by multiple basocellular epitheliomas, keratocysts in the jaws, bifid ribs, palmar and/or plantar pits and ectopic calcifications of the falx cerebri.
Satyaki Ganguly, Kranti C Jaykar, Rajesh Kumar, Abhijeet Kumar Jha, P K Banerjee   +4 more
doaj   +1 more source