Results 41 to 50 of about 1,573 (165)

Nevoid basal cell carcinoma syndrome: A case report

Journal of Dr. NTR University of Health Sciences, 2018
Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant inherited condition that exhibits high penetrance and variable expressivity. The syndrome is caused by mutations in patch (PTCH), a tumor suppressor gene that has been mapped to ...
Venkatesh K Dodda, Sravya Taneeru, Venkateshwara R Guttikonda, Rajsekhar Gaddipati   +3 more
doaj   +1 more source

Gingival enlargement following levetiracetam treatment: A clinical case analysis

Epilepsia Open, Volume 10, Issue 5, Page 1695-1698, October 2025.
Abstract This report describes a 21‐year‐old female with a history of epilepsy, diagnosed at age 17, who developed gingival enlargement after being treated with levetiracetam. Her dosage was titrated to 750 mg twice daily, achieving satisfactory seizure control.
Awadh M. Alahmari, Ali M. Alkhathaami
wiley   +1 more source

Epidermal Nevi and Epidermal Naevus Syndromes

JEADV Clinical Practice, Volume 4, Issue 3, Page 669-680, August 2025.
ABSTRACT Epidermal nevi (EN) arise from postzygotic variants in ectoderm‐derived cell lines, such as keratinocytes and cells forming adnexa. EN may be present alone without any associated abnormality or be part of a syndrome. In this review, we will discuss about the clinical and genetics of the main types of EN and related syndromes.
Gianluca Tadini, Beatrice Carcano, Michela Brena   +2 more
wiley   +1 more source

Two male patients with nevoid basal cell carcinoma syndrome from Turkey

The Turkish Journal of Pediatrics, 2001
Nevoid basal cell carcinoma syndrome, also known as Gorlin's syndrome, is a familial autosomal dominant syndrome characterized by multiple basal cell carcinomas, multiple odontogenic keratocysts of the jaws, and skeletal anomalies. Both tumors and
C Tümer, N Er, S Balci, A Ataç
doaj  

Case report of bilateral ovarian fibromas associated with de novo germline variants in PTCH1 and SMARCA4

Molecular Genetics & Genomic Medicine, 2022
Background Ovarian sex cord‐stromal tumors (OSCTs) are rare ovarian tumors that can develop from sex cord, stromal cells, or both. OSCTs can be benign or malignant.
Tomoyasu Higashimoto, Christy Haakonsen Smith, Mark R. Hopkins, John Gross, Deyin Xing, Jae W. Lee, Traevia Morris, Joann Bodurtha   +7 more
doaj   +1 more source

Cancer therapy resistance from a spatial‐omics perspective

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Spatial omics technologies reveal unprecedented insights into cancer therapy resistance (CTR) by resolving spatial heterogeneity of tumour and microenvironment. This review highlights cutting‐edge spatial omics and computational technologies, showcasing their transformative potential in deciphering CTR mechanisms and uncovering novel diagnostic and ...
Yinghao Zhang, Cheng Yang, Xi Chen, Liang Wu, Zhiyuan Yuan, Fan Zhang, Bin‐Zhi Qian   +6 more
wiley   +1 more source

Role of single‐nucleotide polymorphism microarray in the classification of BAP1‐inactivated melanocytic tumours

Histopathology, Volume 87, Issue 1, Page 110-129, July 2025.
Here we report the features of 24 BAP1‐inactivated melanocytic tumours including 19 BAP1‐inactivated melanocytomas (BIMs) and five BAP1‐inactivated melanomas. BIMs have a favourable prognosis, even those with multiple copy number aberrations (CNAs).
Joseph S. Durgin, Nicholas A. Zoumberos, Taylor Novice, Douglas R. Fullen, Alexandra C. Hristov, Lori Lowe, Rajiv M. Patel, Paul W. Harms, Aleodor A. Andea, Scott C. Bresler   +9 more
wiley   +1 more source

Nevoid basal cell carcinoma syndrome: A case report

Pifu-xingbing zhenliaoxue zazhi
A case of nevoid basal cell carcinoma syndrome is reported. A 47-year-old woman presented with a 10-year history of widespread asymptomatic nodules. Dermatological examination showed multiple hyperpigmented nodules and papules on the face, trunk, and ...
ZHONG Huiting, LIU Ting, CHEN Yanqing, LU Yankun, LI Jianjian, MA Han   +5 more
doaj   +1 more source

Risk of childhood brain tumors after exposure to CT radiation: A nationwide population‐based case–control study in Finland

International Journal of Cancer, Volume 156, Issue 11, Page 2148-2157, 1 June 2025.
What's new? This population‐based case‐control study quantifies the risk of childhood brain tumors following exposure to radiation from computed tomography scans in Finland. Leveraging comprehensive nationwide cancer and computed tomography data and addressing key limitations in previous research, including reverse causation and confounding by ...
Jad Abuhamed, Atte Nikkilä, Jani Raitanen, Olli Lohi, Anssi Auvinen   +4 more
wiley   +1 more source

Nevoid basal cell carcinoma syndrome—case report and genetic study

Journal of Dental Sciences, 2010
Nevoid basal cell carcinoma syndrome (also named Gorlin-Goltz syndrome) is a rare disease. Commonly seen features include multiple odontogenic keratocysts (OKCs), nevus-like basal cell carcinoma, and bifid ribs.
Yu-Feng Huang, Yi-Juai Chen, Hui-Wen Yang   +2 more
doaj   +1 more source