Results 51 to 60 of about 1,573 (165)

Identification of novel candidate predisposing genes in familial nonmedullary thyroid carcinoma implicating DNA damage repair pathways

International Journal of Cancer, Volume 156, Issue 1, Page 130-144, 1 January 2025.
What's new? Susceptibility genes already associated with nonsyndromic familial nonmedullary thyroid carcinoma (FNMTC) account for only a small portion of the disease's genetic burden. Hence, other predisposing genetic alterations are suspected. Here, the authors applied next‐generation sequencing to analyze cancer‐predisposing genes in probands from ...
Carolina Pires, Inês J. Marques, Ana Saramago, Margarida M. Moura, Marta Pojo, Rafael Cabrera, Catarina Santos, Francisco Rosário, Diana Lousa, João B. Vicente, Tiago M. Bandeiras, Manuel R. Teixeira, Valeriano Leite, Branca M. Cavaco   +13 more
wiley   +1 more source

Odontogenic Keratocysts Don't Harbor BRAF Mutation: A Genetic and Immunohistochemical Analysis

Oral Diseases, EarlyView.
Raisa Severino‐Lazo, Jéssica da Silva Cunha, Allan Vinícius Martins‐de‐Barros, Karina Helen Martins, Adauto Gomes Barbosa Neto, Jorge Esquiche León, Marianne de Vasconcelos Carvalho   +6 more
wiley   +1 more source

S2k guideline basal cell carcinoma of the skin (update 2023)

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 22, Issue 12, Page 1697-1714, December 2024.
Summary Basal cell carcinoma is the most common malignant tumor in the fair‐skinned population and its incidence continues to rise. An update of the S2k guideline with the participation of all specialist societies familiar with the clinical picture and previous literature research is of great importance for the quality of care for affected patients. In
Berenice M. Lang, Panagiotis Balermpas, Andrea Bauer, Andreas Blum, Thomas Dirschka, Markus Follmann, Jorge Frank, Bernhard Frerich, Klaus Fritz, Axel Hauschild, Ludwig M. Heindl, Hans‐Peter Howaldt, Stephan Ihrler, Vinodh Kakkassery, Bernhard Klumpp, Albrecht Krause‐Bergmann, Christoph Löser, Markus Meissner, Michael M. Sachse, Max Schlaak, Michael P. Schön, Lutz Tischendorf, Michael Tronnier, Dirk Vordermark, Julia Welzel, Michael Weichenthal, Susanne Wiegand, Roland Kaufmann, Stephan Grabbe   +28 more
wiley   +1 more source

Tissue proteomics repositories for data reanalysis

Mass Spectrometry Reviews, Volume 43, Issue 6, Page 1270-1284, November/December 2024.
Abstract We are approaching the third decade since the establishment of the very first proteomics repositories back in the mid‐'00s. New experimental approaches and technologies continuously enrich the field while producing vast amounts of mass spectrometry data.
Rafael Stroggilos, Aggeliki Tserga, Jerome Zoidakis, Antonia Vlahou, Manousos Makridakis   +4 more
wiley   +1 more source

Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature

BMC Cancer, 2010
Background and Case Presentation A patient with nevoid basal cell carcinoma syndrome (Gorlin syndrome) presented with two unusual clinical features, i.e.
Meyer Günther, Straka Christian, Maßmann Jörg, Sarbia Mario, Prodinger Peter M, Steinlein Ortrud K   +5 more
doaj   +1 more source

Germline PTCH1: c.361_362insAlu alteration identified by comprehensive exome and RNA sequencing in a patient with Gorlin syndrome

American Journal of Medical Genetics Part A, Volume 194, Issue 10, October 2024.
Abstract Gorlin syndrome can be caused by pathogenic/likely pathogenic (P/LP) variants in the tumor suppressor gene PTCH1 (9q22.1‐q31), which encodes the receptor for the sonic hedgehog (SHH) ligand. We present a 12‐month‐old boy clinically diagnosed with Gorlin syndrome who was found to have significantly delayed development, palmar pitting, palmar ...
Aaron Y. Mochizuki, Chinmayee B. Nagaraj, Douglas Depoorter, Kathleen M. Schieffer, Sun Young Kim   +4 more
wiley   +1 more source

Late subsequent leukemia after childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS)

Cancer Medicine, Volume 13, Issue 20, October 2024.
Although subsequent short‐latency leukemias are well described‐among survivors of childhood cancer, late (5–14.9 years from diagnosis) and very late (>15 years from diagnosis) have not been well studied. We assessed prevalence, risk factors, and outcomes for late and very late subsequent leukemias in the Childhood Cancer Survivor Study (CCSS) cohort ...
Taumoha Ghosh, Geehong Hyun, Rikeenkumar Dhaduk, Miriam Conces, Michael A. Arnold, Rebecca M. Howell, Tara O. Henderson, Aaron McDonald, Leslie L. Robison, Yutaka Yasui, Kirsten K. Ness, Gregory T. Armstrong, Joseph P. Neglia, Lucie M. Turcotte   +13 more
wiley   +1 more source

One‐stage prosthodontically driven jaw reconstruction in patients with benign and malignant pathologies: A 7‐ to 11‐year cohort study

Clinical Oral Implants Research, Volume 35, Issue 10, Page 1343-1354, October 2024.
Abstract Objectives One stage functional jaw reconstruction is defined as the resection and reconstruction of segmental defects in conjunction with the placement of dental implants in an ideal prosthetic position and loaded with a provisional restoration, during one surgical procedure.
Vinay V. Kumar, Supriya Ebenezer, Sreelakshmi Viswanath, Andreas Thor   +3 more
wiley   +1 more source

Embryonal and pineal tumours

Cytopathology, Volume 35, Issue 5, Page 561-571, September 2024.
Abstract Embryonal and pineal tumours represent a diverse group of central nervous system (CNS) neoplasms. While many of the small round blue cell tumours that make up the embryonal neoplasms share similar histologic qualities, there are several morphologic and cytologic characteristics that are useful in distinguishing different tumour types ...
Joseph Reznicek, Nima Sharifai, Pouya Jamshidi, Nitin Wadhwani, Jared T. Ahrendsen   +4 more
wiley   +1 more source

Medulloblastoma and other neoplasms in patients with heterozygous germline SUFU variants: A scoping review

American Journal of Medical Genetics Part A, Volume 194, Issue 6, June 2024.
Abstract In 2002, heterozygous suppressor of fused variants (SUFU+/−) in the germline were described to have a tumor suppressor role in the development of pediatric medulloblastoma (MB). Other neoplasms associated with pathologic germline SUFU+/− variants have also been described among patients with basal cell nevus syndrome (BCNS; BCNS is also known ...
Stephanie G. Lee, Gareth Evans, Maddie Stephen, Rachel Goren, Melissa Bondy, Steven Goodman   +5 more
wiley   +1 more source