Results 61 to 70 of about 7,017,185 (188)

Case report of bilateral ovarian fibromas associated with de novo germline variants in PTCH1 and SMARCA4

Molecular Genetics & Genomic Medicine, 2022
Background Ovarian sex cord‐stromal tumors (OSCTs) are rare ovarian tumors that can develop from sex cord, stromal cells, or both. OSCTs can be benign or malignant.
Tomoyasu Higashimoto, Christy Haakonsen Smith, Mark R. Hopkins, John Gross, Deyin Xing, Jae W. Lee, Traevia Morris, Joann Bodurtha   +7 more
doaj   +1 more source

Multiple Odontogenic Keratocysts as the Initial Manifestation of Gorlin Syndrome in a Child: A Case Report With Conservative Management and Diagnostic Considerations

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
Multiple odontogenic keratocysts are one of the major diagnostic criteria of Gorlin syndrome and may represent an early manifestation of the disorder in pediatric patients. This report describes the diagnostic process and management of an 11‐year‐old boy who presented with multiple mandibular cystic lesions associated with displacement of developing ...
V. Anguera-Ortega, P. Cahuana-Bartra, L. Brunet-Llobet, Y. González-Chópite, E. I. Mashala, J. Miranda-Rius, Priya Gusain   +6 more
wiley   +1 more source

Recurrent Odontogenic Keratocyst Mimicking Persistent Periapical Lesion in the Anterior Maxilla: A Case Report With 15‐year follow up

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
Odontogenic keratocysts (OKCs) are aggressive odontogenic cysts with a high recurrence rate, often presenting diagnostic challenges due to their ability to mimic common periapical pathologies. Although more prevalent in the mandible, maxillary OKCs, especially those resembling periapical lesions, are rare and prone to misdiagnosis.
Sumaya O. Basudan, Jose Francisco Gomez-Sosa   +1 more
wiley   +1 more source

Syndromic Multiple Odontogenic Keratocysts Associated With Impacted Teeth: A Rare Case Report

Case Reports in Dentistry, Volume 2026, Issue 1, 2026.
Introduction Odontogenic keratocysts are developmental odontogenic cysts that may occur as solitary lesions or as multiple jaw lesions. Multiple odontogenic keratocysts in young patients should raise suspicion of an underlying syndrome, particularly Gorlin–Goltz syndrome.
Faizal Manrapi, Mohammad Gazali, Nurwahida, Nisrina Ekayani Nasrun, Hannah Wesley   +4 more
wiley   +1 more source

Combination therapy of basal-cell carcinoma in 31-year-old patient with nevoid basal cell carcinoma syndrome - case study [PDF]

, 2016
Nevoid basal cell carcinoma syndrome (NBCCS) is a rare genetic disease that is manifested in a number of disorders concerning the skin, skeleton, cardiovascular and nervous systems.
Raszewska-Famielec, Magdalena, Pilat, Joanna, Dudra-Jastrzębska, Monika, Pilat, Paweł, Borzecki, Adam   +4 more
core  

Comprehensive Insights Into Basal Cell Carcinoma: Causes, Presentation, Prevention, and Modern Therapeutic Approaches

Cancer Medicine, Volume 14, Issue 24, December 2025.
This article provides a comprehensive overview of basal cell carcinoma (BCC), focusing on innovative non‐surgical prevention and treatment protocols. It introduces a novel, practitioner‐friendly algorithm for BCC management, offering clear guidance for selecting treatment based on patient profiles and tumor characteristics.
Sophia Levit, Joshua Shoykhet, Eyal Levit   +2 more
wiley   +1 more source

Gingival enlargement following levetiracetam treatment: A clinical case analysis

Epilepsia Open, Volume 10, Issue 5, Page 1695-1698, October 2025.
Abstract This report describes a 21‐year‐old female with a history of epilepsy, diagnosed at age 17, who developed gingival enlargement after being treated with levetiracetam. Her dosage was titrated to 750 mg twice daily, achieving satisfactory seizure control.
Awadh M. Alahmari, Ali M. Alkhathaami
wiley   +1 more source

Fine genetic mapping of the gene for nevoid basal cell carcinoma syndrome

, 1994
Nevoid basal cell carcinoma syndrome (NBCCS, or Gorlin syndrome) is a cancer predisposition syndrome characterized by multiple basal cell carcinomas and diverse developmental defects.
Wainwright B., Wicking C., Chenevix-Trench G., Berkman J.   +3 more
core   +1 more source

Epidermal Nevi and Epidermal Naevus Syndromes

JEADV Clinical Practice, Volume 4, Issue 3, Page 669-680, August 2025.
ABSTRACT Epidermal nevi (EN) arise from postzygotic variants in ectoderm‐derived cell lines, such as keratinocytes and cells forming adnexa. EN may be present alone without any associated abnormality or be part of a syndrome. In this review, we will discuss about the clinical and genetics of the main types of EN and related syndromes.
Gianluca Tadini, Beatrice Carcano, Michela Brena   +2 more
wiley   +1 more source

Cancer therapy resistance from a spatial‐omics perspective

Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Spatial omics technologies reveal unprecedented insights into cancer therapy resistance (CTR) by resolving spatial heterogeneity of tumour and microenvironment. This review highlights cutting‐edge spatial omics and computational technologies, showcasing their transformative potential in deciphering CTR mechanisms and uncovering novel diagnostic and ...
Yinghao Zhang, Cheng Yang, Xi Chen, Liang Wu, Zhiyuan Yuan, Fan Zhang, Bin‐Zhi Qian   +6 more
wiley   +1 more source