Results 41 to 50 of about 664,036 (261)

Blue nevus with a starburst pattern on dermoscopy

Dermatology Practical & Conceptual, 2012
An 11-year-old girl presented to our department with a blue-gray papule approximately 4 mm in diameter. We suspected that it was a blue nevus or a pigmented Reed/Spitz nevus.
Takeo Shiga, Kimiko Nakajima, Masahito Tarutani, Miki Izumi, Masaru Tanaka, Shigetoshi Sano   +5 more
doaj   +1 more source

BRAF wild-type melanoma in situ arising in a BRAF V600E mutant dysplastic nevus [PDF]

, 2015
IMPORTANCE The BRAF V600E mutation accounts for the majority of BRAF mutations found in cutaneous melanoma and is also commonly found in nevi. We used dermoscopy-targeted sampling and a microbiopsy device coupled with DNA sequence analysis to highlight ...
Flewell-Smith, Ross, Jagirdar, Kasturee, Lambie, Duncan, Lin, Lynlee L., Prow, Tari W., Schaider, Helmut, Soyer, H. Peter, Sturm, Richard A., Tan, Jean-Marie   +8 more
core   +1 more source

Melanoma [PDF]

, 2012
Melanoma is a relatively common neoplasm which is increasing in incidence. Melanoma appears as a variegated irregular maculopapular lesion usually on the skin, but possibly on mucosae, conjunctiva, orbit, nails and oesophagus. They may be black, brown,
Magri, Stephanie, Pace, Keith
core   +1 more source

Metastatic melanoma with features of blue nevus and tumoral melanosis identified during pembrolizumab therapy

JAAD Case Reports, 2017
Metastatic melanoma may exhibit clinical or histologic features of blue nevus. Pembrolizumab therapy is associated with regression and tumoral melanosis.
Matthew F. Helm, MD, Michael J. Bax, MD, Paul N. Bogner, MD, Catherine G. Chung, MD   +3 more
doaj   +1 more source

Genetics of melanoma progression: the rise and fall of cell senescence. [PDF]

, 2016
There are many links between cell senescence and the genetics of melanoma, meaning both familial susceptibility and somatic-genetic changes in sporadic melanoma.
Al-Khalaf, Albino, Alimonti, Alonso, Anders, Aoude, Aoude, Artandi, Bandyopadhyay, Bandyopadhyay, Barrett, Bartkova, Bastian, Bastian, Bataille, Bell, Ben-Porath, Bennett, Bennett, Bennett, Berger, Bevona, Bond, Boyle, Cairney, Campisi, Cao, Carvajal, Carvalho, Chandler, Chen, Chien, Christensen, Chudnovsky, Clark, Conde-Perez, Coppé, Coppé, Corre, Curtin, Curtin, Cust, Dankort, Delmas, DePinho, Dhomen, Ding, Dono, Easty, Forbes, Freund, Fujimoto, Fung, Garrido, Gembarska, Gisselsson, Glaessl, Goldstein, Gray-Schopfer, Griewank, Gruis, Ha, Ha, Hanahan, Hayflick, Heaphy, Helgadottir, Herbig, Herbig, Hewitt, Hodis, Hoek, Horn, Huang, Hurk, Hussussian, Iles, Jacobs, Jacobs, Jeck, Johmura, Jönsson, Kraehn, Krauthammer, Krauthammer, Kuilman, Kuilman, Lade-Keller, Lam, Laoukili, Lawrence, Lin, Lin, Londono-Vallejo, MacKenzie Ross, Martínez, Michaloglou, Mooi, Moore, Muñoz-Espín, Nagel, Nan, Narita, Newton-Bishop, Nogueira, Ogbah, Ohanna, Overhoff, Passos, Patton, Pavey, Pawlikowski, Petti, Poliakov, Pollock, Prickett, Reddel, Ressler, Rhee, Robert, Robles-Espinoza, Rode, Rossiello, Rovillain, Ruas, Ruhe, Salama, Sargen, Sato, Serrano, Shay, Shi, Shitara, Snoo, Soengas, Soo, Stark, Stefanaki, Stratton, Straume, Suram, Sviderskaya, Sviderskaya, Sviderskaya, The Cancer Genome Atlas Network, Topping, Tran, Treszl, Tsao, Von Zglinicki, Vredeveld, Wansleben, Wellbrock, Wen, Widmer, Worm, Xia, Xiong, Zhang, Zhu   +159 more
core   +1 more source

Optical Coherence Tomography Angiography of Iris Nevus: A Case Report [PDF]

, 2016
Iris nevus is common: 6% of patients with suspected iris melanoma have lesions other than melanoma, and 36% of them are nevi. Iris nevus turns into melanoma in approximately 8% of cases at a mean of 15 years.
Allegrini, D., Montesano, G., Pece, A.
core   +3 more sources

The importance of p16 and CD117 expression in melanocytic lesions

Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, 2021
Aim: The present study aims to determine the p16 and CD117 expression profiles of melanocytic lesions to investigate immune profiles that may facilitate differential diagnosis of melanoma from benign or potential precursor melanocytic lesions.Materials ...
Sevil Karabağ, Ayşegül İsal Arslan
doaj   +1 more source

Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells. [PDF]

, 2014
BACKGROUND: The importance of the genetic background of cancer cells for the individual susceptibility to cancer treatments is increasingly apparent.
Arozarena, Imanol, Erice, O., Ferguson, J., Goicoechea, I., Margison, G.P., Wellbrock, C.   +5 more
core   +2 more sources

Diagnosis of oral pigmentations and malignant transformations [PDF]

, 1951
BackgroundOral pigmentation is a common finding in the mouth. Pigmentation can be either normal or abnormal discoloration of oral mucous membrane.
Eisen, Kleinegger, Gaeta, Hemminki, Hemminki, Hemminki, McGrath, Kauzman, Dereure, Birek, Kim, Weathers, Buchner, Gupta, Zaraa, Esen, Halder, Hedin, Hedin, Axell, Araki, Perusse, Marks, McAllan, Savage, Westbury, Meyerson, Buchner, Hicks, Goode, Whitt, Barker, Gorsky   +32 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source