Results 41 to 50 of about 637,894 (240)
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest [PDF]
Oncogene-induced senescence (OIS) is a tumor suppression mechanism that blocks cell proliferation in response to oncogenic signaling. OIS is frequently accompanied by multinucleation; however, the origin of this is unknown.
Adams, Peter D.+20 more
core +2 more sources
Abstract Blue nevus is one of the melanotic lesions that can incidentally arise in the prostate gland. A literature review identified 28 previously reported cases, and although rare, the blue nevus appeared to be the commonest melanocytic lesion arising in the prostate. The differential diagnosis includes melanosis and malignant melanoma,
Omar Hameed, Virginia L. Dailey
openaire +3 more sources
Improved discrimination of melanotic schwannoma from melanocytic lesions by combined morphological and GNAQ mutational analysis [PDF]
The histological differential diagnosis between melanotic schwannoma, primary leptomeningeal melanocytic lesions and cellular blue nevus can be challenging.
AV Vallat-Decouvelaere+34 more
core +6 more sources
Estimation and Regularization Techniques for Regression Models with Multidimensional Prediction Functions [PDF]
Boosting is one of the most important methods for fitting regression models and building prediction rules from high-dimensional data. A notable feature of boosting is that the technique has a built-in mechanism for shrinking coefficient estimates and
Hothorn, Torsten+3 more
core +2 more sources
Metastatic melanoma may exhibit clinical or histologic features of blue nevus. Pembrolizumab therapy is associated with regression and tumoral melanosis.
Matthew F. Helm, MD+3 more
doaj +1 more source
Acute inhibition of MEK suppresses congenital melanocytic nevus syndrome in a murine model driven by activated NRAS and Wnt signaling [PDF]
Congenital melanocytic nevus (CMN) syndrome is the association of pigmented melanocytic nevi with extra-cutaneous features, classically melanotic cells within the central nervous system, most frequently caused by a mutation of NRAS codon 61.
Adams, P.D.+16 more
core +2 more sources
Melanoma is a relatively common neoplasm which is increasing in incidence. Melanoma appears as a variegated irregular maculopapular lesion usually on the skin, but possibly on mucosae, conjunctiva, orbit, nails and oesophagus. They may be black, brown,
Magri, Stephanie, Pace, Keith
core +1 more source
幼児顔面に発症したcombined nevus (blue nevus & Spitz nevus) の1例
A case was found in a two-year-old girl. The Combined nevus was not visible on her body when she was born. Around six months after birth, a black spot started to appear on the outside of her right eyebrow. The size of the black spot was measured at 5×4mm
裕一 鈴木+2 more
semanticscholar +1 more source
A case of blue rubber bleb nevus syndrome [PDF]
Blue rubber bleb nevus syndrome is a rare disorder that is characterized by multiple recurrent vascular malformations, such as hemangioma, and these primarily involve the skin and the gastrointestinal tract.
Bak+28 more
core +2 more sources
Blue rubber bleb nevus syndrome coexisted with intestinal intussusception: a case report [PDF]
Blue Rubber Bleb Nevus Syndrome (BRBNS) is an uncommon congenital disorder characterized by sporadic venous malformation which mainly occurs in skin and alimentary canal.
Wang, Yuanjie+2 more
core +2 more sources