Results 81 to 90 of about 353,225 (233)
A Case of Pediatric Spitz Melanoma With a ZEB2::ALK Fusion
ABSTRACT We present a rare case of Spitz melanoma in a 3‐year‐old male patient with a ZEB2::ALK fusion. This ALK‐fused tumor exhibited aggressive behavior, recurring after an initial wide local excision and progressing despite neoadjuvant immunotherapy with a PD‐1 inhibitor.
Nathanael C. Jensen +3 more
wiley +1 more source
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour +6 more
wiley +1 more source
Conjunctival blue nevus in a child – Case report and review of literature
Purpose: To report a rare case of a conjunctival blue nevus in a child. Observations: A 10-year-old girl underwent an excisional biopsy for an atypical growing melanocytic conjunctival lesion.
Yasser Yahya +5 more
doaj +1 more source
ABSTRACT Background Fine‐needle aspiration biopsy (FNAB) is the preferred first‐line diagnostic tool for evaluating lymphadenopathy due to its minimally invasive nature and cost‐effectiveness. However, cytopathological interpretation of lymph node FNAB remains challenging because of the wide morphological spectrum of lymphoid lesions.
Immacolata Cozzolino +5 more
wiley +1 more source
This review critically examines clinical studies on both conventional and machine learning (ML)‐integrated diffuse optical spectroscopy and imaging methods for dermatological applications, with a primary focus on the past decade and inclusion of earlier foundational work where appropriate.
Iftak Hussain +7 more
wiley +1 more source
When Pigment Loss Meets Pigment Clusters: Vitiligo in a Congenital Speckled Lentiginous Nevus
Vitiligo, an acquired disorder, manifests as depigmented patches on the skin due to the selective destruction of melanocytes. Congenital speckled lentiginous nevus (CSLN), also known as nevus spilus, is a benign pigmented skin lesion present at birth or ...
Vivek Narendrasingh Salame +3 more
doaj +1 more source
ABSTRACT Lentigines, café‐au‐lait macules (CALMs), and vitiligo are pigmentary disorders that seldom occur together in a single individual. Their co‐occurrence may indicate underlying genetic syndromes requiring differential diagnosis. We report an 18‐year‐old male who developed CALMs at age 11, agminated lentigines at age 13, and vitiligo on the right
Xinxin Lei, Bo Xie
wiley +1 more source
A deep learning–clinical nomogram hybrid for predicting sentinel lymph node metastasis in melanoma
We developed MISSLE, a deep learning–clinical nomogram hybrid model, to predict sentinel lymph node metastasis in invasive cutaneous melanoma with a high area under the receiver operating characteristic curve of 0.950 on the test set. MISSLE identifies key histopathological features and integrates AI for improved clinical decision‐making.
Minh‐Khang Le +8 more
wiley +1 more source
Global consensus on the management of melanin hyperpigmentation disorders
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron +9 more
wiley +1 more source
[Disseminated pigmented nevus syndrome].
Two patients carriers of a neuro-cutaneous syndrome showing scattered pigmentary nevus and neurologic disorders are exposed, who are added to three similar cases presented in a previous publication. Differences with other syndromes that show cafe-au-lait spots, like those of Recklinghausen and Albright, and also of other known publications, are ...
H N, Cabrera +3 more
openaire +1 more source

