Results 161 to 170 of about 43,459 (265)

The Influence of Extracellular Citrate in Physiological Concentration on the Proliferation of Malignant Melanoma

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.
ABSTRACT Cancer cells rely on citrate for multiple metabolic processes, suggesting that limiting the availability of extracellular citrate may represent a novel therapeutic strategy. The plasma membrane citrate transporter (pmCiC) has been implicated in the pathogenesis of several cancers before, and its activity can be inhibited by gluconate.
Konstantin Drexler   +8 more
wiley   +1 more source

Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment

open access: yesJournal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 423-430, March 2026.
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang   +3 more
wiley   +1 more source

Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 895-913, March 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of new cancer cases, it is projected to become the second leading cause of cancer‐related deaths by 2030.
Muhammad Masroor Hussain   +5 more
wiley   +1 more source

Acral Speckled Lentiginous Nevus. [PDF]

open access: yesCureus
Maverakis Ramirez N   +4 more
europepmc   +1 more source

Near‐Infrared Spectroscopy Combined With Skin Impedance for Detection of Skin Cancer in Primary Care

open access: yesSkin Research and Technology, Volume 32, Issue 3, March 2026.
Abstract Background The established method in primary care to distinguish skin cancer from benign lesions is clinical examination, with or without dermoscopy. The experience among primary care physicians in assessing skin tumours varies, as does the accessibility to teledermoscopy.
Maria Fragkou Dragka   +2 more
wiley   +1 more source

A Comparative Study of Melanocytic Tumours: Linking Portuguese Dogs and Cats to Human Cases

open access: yesVeterinary and Comparative Oncology, Volume 24, Issue 1, Page 105-120, March 2026.
ABSTRACT Melanocytic tumours (MT) occur in both humans and companion animals, presenting an opportunity for comparative oncology research. Thus, this study provides a comprehensive epidemiological analysis comparing MT in Portuguese dogs, cats and humans. Data were obtained from the Portuguese National Cancer Registry (RON) (2011–2021) and Vet‐OncoNet (
Catarina Alves Pinto   +5 more
wiley   +1 more source

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