Novel nano-biosensors for life science systems and their applications in early, accurate, and non-invasive melanoma and other types of cancer detection [PDF]
Melanoma (the 5th and 6th most common cancer in Caucasian males and females, respectively), is the most severe form of skin cancer, which is often fatal if recognized in its advanced stage.
Bockrath, Marc+2 more
core +1 more source
Linear verrucous epidermal nevus with oral manifestations: report of two cases [PDF]
Linear verrucous epidermal nevi (LVEN) are characterized by verrucous papules often coalescing into well-demarcated skin-colored or brown plaques following the lines of Blaschko.
Gomes, Rafael Tomaz+4 more
core
A 35-year-old woman presented with cosmetically disturbing facial plaques, which had been present since birth and were consistent with nevus sebaceus on histopathologic examination. Nevus sebaceus is a congenital, hairless plaque, which is found most commonly on the scalp and face and typically becomes thicker and more verrucous in appearance as the ...
Kovich, Olympia, Hale, Elizabeth K
openaire +4 more sources
Prevalensi dan Gambaran Histopatologi Nevus Pigmentosus di Bagian Patologi Anatomi Rumah Sakit Dr. Mohammad Hoesin Palembang Periode 1 Januari 2009-31 Desember 2013 [PDF]
Nevus pigmentosus adalah tumor jinak yang berasal dari melanosit, yaitu sel dendritik yang menghasilkan pigmen, secara normal terdapat di antara keratinosit pada lapisan basal epidermis.
Aspitriani, A. (Aspitriani)+2 more
core +2 more sources
Estimation and Regularization Techniques for Regression Models with Multidimensional Prediction Functions [PDF]
Boosting is one of the most important methods for fitting regression models and building prediction rules from high-dimensional data. A notable feature of boosting is that the technique has a built-in mechanism for shrinking coefficient estimates and
Hothorn, Torsten+3 more
core +2 more sources
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
A rare case of melanosis of the hard palate mucosa in a patient with chronic myeloid leukemia [PDF]
Imatinib Mesylate, also known as Gleevec or ST1-571, is a tyrosine-kinase inhibitor used as the gold standard medication for the chronic myeloid leukemia (CML); Imatinib has indeed deeply revolutionized the CML therapy allowing most patients to have a ...
Bosco, Daniela+4 more
core +3 more sources
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
An Unusual Melanocytic Nevus of Conjunctiva : Balloon Cell Nevus [PDF]
Melanocytic nevi are one of the most common benign tumors of the conjunctiva. The balloon cell nevus is a rare and unusual variant of nevus of melanocytic origin, in which more than 50% of the tumor is composed of large polygonal cells with small nucleus
Geethalakshmi, U+3 more
core
Melanomas and nevi share many of the same growth-promoting mutations. However, melanomas grow relentlessly while benign nevi eventually undergo growth arrest and stabilize. The difference in their long-term growth potential may be attributed to activation of cellular senescence pathways.
Andrew L. Ross+2 more
openaire +2 more sources