Results 71 to 80 of about 43,716 (267)
The correlation between uveal melanoma and iris nevus
Holistic Integrative OncologyPurpose To investigate the impact of iris nevus on the incidence and prognosis of uveal melanoma (UM). Methods A retrospective cohort study was conducted involving 1128 UM cases and 4356 healthy controls. Participants were categorized based on iris nevus
Yuhang Yang +5 more
doaj +1 more source
Nevus of Ota with Rare Palatal Involvement: A Case Report with Emphasis on Differential Diagnosis
Case Reports in Dentistry, 2011 Nevus of Ota, a dermal melanocytic nevus, is rare in the Indian subcontinent. It presents as a brown, blue, or gray patch on the face and is within the distribution of the ophthalmic and maxillary branches of the trigeminal nerve.
Gaurav Sharma, Archna Nagpal
doaj +1 more source
Disruption of Vitamin D and Calcium Signaling in Keratinocytes Predisposes to Skin Cancer. [PDF]
, 2016 1,25 dihydroxyvitamin D (1,25(OH)2D), the active metabolite of vitamin D, and calcium regulate epidermal differentiation. 1,25(OH)2D exerts its effects through the vitamin D receptor (VDR), a transcription factor in the nuclear hormone receptor family ...
Bikle, Daniel D +4 more
core +2 more sources
ISRN Dermatology, 2011 Melanomas and nevi share many of the same growth-promoting mutations. However, melanomas grow relentlessly while benign nevi eventually undergo growth arrest and stabilize. The difference in their long-term growth potential may be attributed to activation of cellular senescence pathways.
Andrew L. Ross +2 more
openaire +2 more sources
JEADV Clinical Practice, EarlyView.ABSTRACT Background Melanoma accounts for more than 75% of skin cancer‐related mortality. Dermatoscopy is an evidence‐based technique for earlier detection, yet differentiating melanocytic lesions remains challenging. Sub‐UV reflectance dermatoscopy (sUVRD) uses purple light (405 nm) to visualise chromophore distribution in the skin.
L. Dupont +9 more
wiley +1 more source
Multiple Large Cysts Arising from Nevus [PDF]
Archives of Plastic Surgery, 2012 Nevus comedonicus is a type of hamartoma that arises from a developmental anomaly of themesodermal part of the pilosebaceous gland. In most cases of nevus comedonicus, an acnelikeskin condition develops.
Sang-Yeop Yi +4 more
doaj
Eccrine Poroma Arising within Nevus Sebaceous
Case Reports in Dermatology, 2016 Nevus sebaceous is a congenital, benign hamartomatous lesion, characterized by a yellowish to skin-colored, hairless, verrucous plaque on the head and neck region.
Natnicha Girdwichai +2 more
doaj +1 more source
Label-free high-throughput photoacoustic tomography of suspected circulating melanoma tumor cells in patients in vivo [PDF]
, 2020 Significance: Detection and characterization of circulating tumor cells (CTCs), a key determinant of metastasis, are critical for determining risk of disease progression, understanding metastatic pathways, and facilitating early clinical intervention.
Cornelius, Lynn A. +6 more
core +1 more source
In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells [PDF]
, 2015 Oncogenic signaling in melanocytes results in oncogene-induced senescence (OIS), a stable cell-cycle arrest frequently characterized by a bi- or multinuclear phenotype that is considered as a barrier to cancer progression.
Bröcker, E.-B. +12 more
core +2 more sources
Should Dermatologists Recommend Direct‐to‐Consumer App‐Based Remote Diagnostics? An Ethical Analysis
JEADV Clinical Practice, EarlyView.ABSTRACT Background Dermatology patients still face barriers in accessing timely specialist care. As direct‐to‐consumer (DTC) apps for remote dermatological diagnostics proliferate, guidance is lacking. While promising efficiency and efficacy, their clinical—and ethical—legitimacy is not yet well established.
Sonja Mathes +9 more
wiley +1 more source