Results 251 to 260 of about 10,524,681 (309)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
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2016
Debunking the myth of the ageing time bomb, this timely book from the authors of <i>Retiring with Attitude</i> challenges our assumptions and stereotypes and demonstrates that we are capable of living better together longer in this new, older world.
Caroline Lodge +2 more
openaire +1 more source
Debunking the myth of the ageing time bomb, this timely book from the authors of <i>Retiring with Attitude</i> challenges our assumptions and stereotypes and demonstrates that we are capable of living better together longer in this new, older world.
Caroline Lodge +2 more
openaire +1 more source
Neurology, 2022
The pandemic is transforming neurology. Long COVID will linger, neurologic diseases will increase, and technology, artificial intelligence, and new virtual worlds will usher a new age of the brain and new roles for neurologists. The pandemic has compelled international collaboration, greatly increased communications, and accelerated drug and vaccines ...
openaire +2 more sources
The pandemic is transforming neurology. Long COVID will linger, neurologic diseases will increase, and technology, artificial intelligence, and new virtual worlds will usher a new age of the brain and new roles for neurologists. The pandemic has compelled international collaboration, greatly increased communications, and accelerated drug and vaccines ...
openaire +2 more sources
Positive aging: New images for a new age
Ageing International, 2001The gerontological literature in the social sciences has typically characterized the aging process in terms of decline, degeneration, and decrepitude. Comparatively little attention has been paid to the possibility of growth, generativity, and development in the last decades of life.
Gergen, M. M., Gergen, Kenneth J.
openaire +2 more sources
Current Infectious Disease Reports, 2001
Prostatitis has long been a poorly understood and poorly characterized entity. Characterized in 1980 as a "wastebasket of clinical ignorance," it has only recently begun to be studied effectively. Prostatitis represents over 2 million medical office visits per year in the United States, and is the diagnosis given to 8% of urology clinic patients.
Granville L., Lloyd +1 more
openaire +2 more sources
Prostatitis has long been a poorly understood and poorly characterized entity. Characterized in 1980 as a "wastebasket of clinical ignorance," it has only recently begun to be studied effectively. Prostatitis represents over 2 million medical office visits per year in the United States, and is the diagnosis given to 8% of urology clinic patients.
Granville L., Lloyd +1 more
openaire +2 more sources
The Lancet, 1980
Blood-nicotine levels were measured during non-inhaled cigar smoking and after taking snuff. The rate of nicotine absorption from non-inhaled cigar smoking was slow. This may explain why many cigarette smokers continue to inhale when they switch to cigars. In contrast, the rate of absorption from snuff was extremely rapid.
M A, Russell, M J, Jarvis, C, Feyerabend
openaire +2 more sources
Blood-nicotine levels were measured during non-inhaled cigar smoking and after taking snuff. The rate of nicotine absorption from non-inhaled cigar smoking was slow. This may explain why many cigarette smokers continue to inhale when they switch to cigars. In contrast, the rate of absorption from snuff was extremely rapid.
M A, Russell, M J, Jarvis, C, Feyerabend
openaire +2 more sources
The new age of pharmacovigilance
Medical Journal of Australia, 2009The Therapeutic Goods Administration is strengthening pharmacovigilance, but strategies to encourage the conduct of pharmacoepidemiological research in Australia are needed.
openaire +2 more sources
Globalizing IN for the new age
IEEE Communications Magazine, 1993The future directions of intelligent network (IN) enhancements are discussed. The reasons why globalization of service provisions based on IN technology will be indispensable are also discussed. The functions required for global INs are analyzed. Possible schemes for IN function distributions are identified. The functions that should be centralized and
Masanobu Fujioka +3 more
openaire +1 more source