Results 101 to 110 of about 6,634,227 (307)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Whip Rule Breaches in a Major Australian Racing Jurisdiction: Welfare and Regulatory Implications

open access: yesAnimals, 2017
Whip use in horseracing is increasingly being questioned on ethical, animal welfare, social sustainability, and legal grounds. Despite this, there is weak evidence for whip use and its regulation by Stewards in Australia.
Jennifer Hood   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Purification Method of Exchangeable Cations of Calcium Bentonite

open access: yesKuangchan zonghe liyong
The properties of bentonite are influenced by the type and content of exchangeable cations. The content of single-type cations can be increased by purification, thereby improving the properties of bentonite (such as the properties of adsorption ...
Xueying PAN   +5 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Rewriting the genetic code. [PDF]

open access: yesScience, 2021
Jewel D, Chatterjee A.
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Behavioral observations of the endangered Rio Grande silvery minnow in a conservation aquaculture facility

open access: yesCroatian Journal of Fisheries, 2018
A major reason why conservation aquaculture is needed to improve the success of aquaculture-assisted fisheries is that traditional production aquaculture produces fish with mal-adaptive behaviors.
Tave Douglas   +2 more
doaj   +1 more source

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