Results 111 to 120 of about 29,602,681 (295)

The Impact of Contemporary Glucagon-like Peptide-1 Receptor Agonists on the Onset, Severity, and Conversion to Arthroplasty in Hip and Knee Osteoarthritis

Orthopaedic Journal of Sports Medicine
Background: The growing popularity of glucagon-like peptide-1 receptor agonists (GLP-1-RAs) for weight loss could significantly impact joint preservation and arthroplasty.
Joshua R. Porto MS, Monish S. Lavu MHM, Christian J. Hecht BS, David C. Kaelber MD, PhD, MPH, Peter K. Sculco MD, Nathanael D. Heckmann MD, Atul F. Kamath MD, MBA   +6 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Analysis and Forecasting of Anesthesia Manpower in Cuyahoga County, Ohio

Operations Research ...
Reisman, A. (Creatorcre), Lewy, P. M. (Creatorcre), Kaujalgi, V. B. (Creatorcre), Esogbue, A. O. (Creatorcre), Dean, B. V. (Creatorcre), Aggarwal, V. V. (Creatorcre), Gravenstein, J. S. (Creatorcre)   +6 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Application of Management Science Techniques to Dental Practice Management

Operations Research ...
Emmons, Hamilton (Creatorcre), Reisman, Arnold (Creatorcre), Rivaud, Juan (Creatorcre), Green, Edward J. (Creatorcre), Morito, Susumu (Creatorcre)   +4 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Analysis of the Reserve Book System at the Health Center Library

Operations Research ...
Mehta, Shailesh (Creatorcre), Darukhanavala, Phiroz P. (Creatorcre), Shroff, Pradip H. (Creatorcre), Dadachanji, Keki R. (Creatorcre)   +3 more
core  

The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming

eLife
Acute myocardial infarction (MI) is a leading cause of morbidity and mortality, and therapeutic options remain limited. Endogenously generated nitric oxide (NO) is highly cardioprotective, but protection is not replicated by nitroso-vasodilators (e.g ...
Zachary W Grimmett, Rongli Zhang, Hua-Lin Zhou, Qiuying Chen, Dawson Miller, Zhaoxia Qian, Justin Lin, Riti Kalra, Steven S Gross, Walter J Koch, Richard T Premont, Jonathan S Stamler   +11 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Association of Individual Characteristics with Success and Failure of U. S. Army Recruiters

Operations Research ...
Coleman, F. David (Creatorcre)
core