Results 91 to 100 of about 29,602,681 (295)
Application of Operations Research in Research Planning - A Case Study
Operations Research ...
Johnson, E. (Creatorcre)
core
Analysis of the Distribution of Private Research Funding to Sports Medicine Orthopaedic Surgeons
Background: The Physician Payments Sunshine Act mandated the public reporting of all industry payments above a $10 value that are disbursed to physicians in the United States.
Aakash K. Shah BA +6 more
doaj +1 more source
Human bed bug infestations have undergone a recent global resurgence. The human antiparasitic drug ivermectin has been proposed as a strategy to help control bed bug infestations, but in vivo data are lacking.
Gale E. Ridge +6 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Operations Research Reports. Statement on Potentially Harmful Content: Digital Case provides access to historical and primary sources that may include language or content that is outdated, biased, offensive, or harmful.
Agnew, Malcolm J. (Creatorcre) +1 more
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
All-Integer Integer Programming Algorithms Applied to Tableaux with Rational Coefficients
Operations Research ...
Salkin, Harvey M. (Creatorcre) +2 more
core
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source

