Results 91 to 100 of about 1,647,803 (316)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Systematics of Guntheria Womersley, 1939 and related genera of chigger mites (Acariformes: Trombiculidae)

open access: yesPersian Journal of Acarology
Chigger mites of the tribe Schoengastiini Vercammen-Grandjean, 1960 having five non-specialized setae on the palpal tarsus and some other genera related to Guntheria Womersley, 1939 were reviewed based on literature.
Alexandr A Stekolnikov
doaj   +1 more source

NEW GOUT CLASSIFICATION CRITERIA (ACR/EULAR 2015)

open access: yesАрхивъ внутренней медицины, 2016
Gout new diagnostic criteria are reflected in the presented translation of new international guidelines (ACR/EULAR 2015).
N. T. Vatutin   +2 more
doaj   +1 more source

A new species of mudfish, Neochanna (Teleostei: Galaxidae), from northern New Zealand

open access: yes, 2001
A new species of mudfish, Neochanna, is described from Northland. Neochanna heleios n.sp. is known from only three ephemeral wetland sites on the Kerikeri volcanic plateau and is abundant only at the type locality.
Gleeson, Dianne M.   +3 more
core   +1 more source

AMPSO: A new Particle Swarm Method for Nearest Neighborhood Classification [PDF]

open access: yes, 2009
Nearest prototype methods can be quite successful on many pattern classification problems. In these methods, a collection of prototypes has to be found that accurately represents the input patterns.
Galván, Inés M.   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A new classification of post-sternotomy dehiscence

open access: yesBrazilian Journal of Cardiovascular Surgery, 2015
The dehiscence after median transesternal sternotomy used as surgical access for cardiac surgery is one of its complications and it increases the patient's morbidity and mortality. A variety of surgical techniques were recently described resulting to the
Jaime Anger   +3 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

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