Results 91 to 100 of about 1,647,803 (316)
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Chigger mites of the tribe Schoengastiini Vercammen-Grandjean, 1960 having five non-specialized setae on the palpal tarsus and some other genera related to Guntheria Womersley, 1939 were reviewed based on literature.
Alexandr A Stekolnikov
doaj +1 more source
NEW GOUT CLASSIFICATION CRITERIA (ACR/EULAR 2015)
Gout new diagnostic criteria are reflected in the presented translation of new international guidelines (ACR/EULAR 2015).
N. T. Vatutin +2 more
doaj +1 more source
A new species of mudfish, Neochanna (Teleostei: Galaxidae), from northern New Zealand
A new species of mudfish, Neochanna, is described from Northland. Neochanna heleios n.sp. is known from only three ephemeral wetland sites on the Kerikeri volcanic plateau and is abundant only at the type locality.
Gleeson, Dianne M. +3 more
core +1 more source
AMPSO: A new Particle Swarm Method for Nearest Neighborhood Classification [PDF]
Nearest prototype methods can be quite successful on many pattern classification problems. In these methods, a collection of prototypes has to be found that accurately represents the input patterns.
Galván, Inés M. +2 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A new classification of post-sternotomy dehiscence
The dehiscence after median transesternal sternotomy used as surgical access for cardiac surgery is one of its complications and it increases the patient's morbidity and mortality. A variety of surgical techniques were recently described resulting to the
Jaime Anger +3 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source

