Results 121 to 130 of about 1,350,060 (249)

Integrating Quadrimalleolar Fractures of the Ankle in a Johannesburg Academic Center: A New Classification. [PDF]

Cureus
Nkosi C, Kyei P, Kagodora B.
europepmc   +1 more source

Aortic stenosis: new classification.

Journal of the American College of Cardiology, 2012
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Early prediction of bronchopulmonary dysplasia using new classification in high-risk preterm infants. [PDF]

Clin Exp Pediatr
Jeon GW.
europepmc   +1 more source

New GOLD classification

Rationale: Little is known about the longitudinal changes associated with using the 2013 update of the multidimensional GOLD strategy for chronic obstructive pulmonary disease (COPD).Objective: To determine the COPD patient distribution of the new GOLD proposal and evaluate how this classification changes over one year compared with the previous GOLD ...
Casanova, Ciro||, Marín, Jose M.||, Martínez-González, Cristina||, de Lucas-Ramos, Pilar||, Mir-Viladrich, Isabel, Cosio, Borja G.||, Peces-Barba, German||, Calle Rubio, Myriam||, Solanes García, Ingrid||, Agüero, Ramón, De Diego-Damia, Alfredo, Feu-Collado, Núria, Alfageme, Inmaculada||, Irigaray, Rosa, Balcells, Eva||, Llunell, Antònia, Galdiz, Juan Bautista, Marín, Margarita, Soler Cataluña, Juan José, Lopez-Campos, José Luis, Soriano, Joan B..||, de-Torres, Juan P., Calvo Bonachera, José, Lacárcel Bautista, Celia, Domenech, Adolfo, Marín Trigo, José María, González, C.M., Piqueras, B.G.C., Cabrera-Lopez, Carlos||, Sánchez Acosta, Alejandro, Abreu González, Juan, Miguel Campos, Elena, Marín, Alicia||, Moreno, Amalia, Márquez Pérez, Francisca Lourdes, Riesco Miranda, Juan Antonio, Rodríguez, Julia Tabara, Golpe, Rafael||, de Miguel Díez, Javier, García Río, Francisco, Díaz Lobato, Salvador   +40 more
openaire   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Fake news classificator

, 2019
Esta investigación se centrará en clasificar las noticias falsas según el estilo y el contenido. Además se implementará un servicio web para realizar predicciones de artículos de contenido en linea y a la vez reentrenarse con los artículos que no ha podido predecir correctamente.
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Excision of proximal fibular aggressive and malignant tumors: a new classification for surgical guidance. [PDF]

Ann Jt
Gao Y, Wang J, Zhang J, Pan F, Shang G.
europepmc   +1 more source