Results 201 to 210 of about 2,993,444 (316)

Ultra-compact fiber tapering: plasmonics and structural bending as new combination of heat and pull. [PDF]

Light Sci Appl, 2023
Yang T.
europepmc   +1 more source

Safety and efficacy of nateglinide/metformin combination therapy in the treatment of type 2 diabetes

, 2008
Marc K Israel1, Eva Istvan2, Michelle A Baron1,31Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA; 2Novartis AG, Basel, Switzerland; 3Sanofi-Aventis, Bridgewater, New Jersey, USAAbstract: The increasing prevalence of type 2 diabetes ...
Marc K Israel, Michelle A Baron, Eva Istvan   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Bertieraacutiflora (Rubiaceae, Bertiereae), a new combination based on the overlooked Psychotriaacutiflora. [PDF]

PhytoKeys
Berger A.
europepmc   +1 more source

Intrapulmonary distribution of blood flow during exercise in pulmonary hypertension assessed by a new combination technique. [PDF]

Front Cardiovasc Med, 2023
Farina S, Pezzuto B, Vignati C, Laveneziana P, Agostoni P.   +4 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

<i>Sinosasadamingshanensis</i> (Poaceae, Bambusoideae), a new combination supported by morphological and molecular evidence. [PDF]

PhytoKeys
Zhang YT, Lin SY, Niu ZY, Jiang WX, Xia NH, Ding YL.   +5 more
europepmc   +1 more source

New species, a new combination, and DNA barcodes of Parachironomus Lenz, 1921 (Diptera, Chironomidae). [PDF]

Zookeys, 2023
Liu WB, Wang Y, Zhao KZ, Wang CY, Zhang JY, Yan CC, Lin XL.   +6 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Two sustainable chromatographic approaches for estimation of new combination of phenylephrine hydrochloride and doxylamine succinate in presence of doxylamine oxidative degradation product. [PDF]

Sci Rep
Abd El-Hadi HR.
europepmc   +1 more source