Results 201 to 210 of about 26,078,541 (291)

Supplementation of a new combination of prebiotic and postbiotic shapes fecal microbiota of old dogs while influencing immune parameters. [PDF]

Sci Rep
Rodiles A, Wambacq W, Le Bourgot C, Cox E, Barbe F, Hesta M, Apper E.   +6 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

 <i>Ligusticopsis shaniana</i>, a new combination separated from <i>Peucedanum</i> sensu lato (Apiaceae) on the basis of morphological and phylogenetic evidence. [PDF]

PhytoKeys
Liu CK, Song BN, Lei JQ, He XJ, Zhou SD.
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

A new combination of a prebiotic and postbiotic mitigates immunosenescence in vaccinated healthy senior dogs. [PDF]

Front Vet Sci
Wambacq WA, Apper E, Le Bourgot C, Barbe F, Lyu Y, Pelst M, Broeckx BJG, Devriendt B, Cox E, Hesta M.   +9 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Revisions to the <i>Gliophorus irrigatus</i> complex (Agaricales, Hygrophoraceae, <i>Gliophorus</i>, section Unguinosae) including four new species, one new combination and comparisons of basidiome vs. eDNA distributions. [PDF]

MycoKeys
Harries DJ, Blencowe CM, Leal-Dutra CA, Lodge DJ, Harrington AH, Bye R, Pearse Z, Russell SD, Williams J, Ré LA, Griffith GW.   +10 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Two new species and a new combination in <i>Aculithus</i> Liu & Li, 2022 (Araneae: Phrurolithidae) from South China. [PDF]

Biodivers Data J
Jiang Z, Wang Z, Lyu X, Yang J, Liu K.
europepmc   +1 more source

Session Laws of New Jersey

Includes an appendix, "Population of the counties, townships and wards in the State of New Jersey, according to the census of 1855." These are tables compiled from the 1855 State ...
New Jersey. Legislature
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