Results 181 to 190 of about 2,993,444 (316)

Drugs and driving in New Zealand: An approach to THC culpability

open access: yes, 2006
For years statistical analysis has been applied to different areas of the natural and applied sciences to determine the degree of confidence that can be placed in research results.
Troncoso Vergara, Carolina
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Traditional Chinese medicine-combination therapies utilizing nanotechnology-based targeted delivery systems: a new strategy for antitumor treatment

open access: yes, 2019
Zhe Ma,1,2 Yuqi Fan,2,3 Yumei Wu,1,2 Dereje Kebebe,1,2,4 Bing Zhang,1,2 Peng Lu,1,2 Jiaxin Pi,1,2 Zhidong Liu1,2 1Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of ...
Kebebe D   +7 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

New combination therapy of praziquantel and <i>Lactobacillus plantarum</i> for enhancing the treatment of clonorchiasis in mice. [PDF]

open access: yesFood Waterborne Parasitol
Ma Y   +13 more
europepmc   +1 more source

A Winning New Combination? Toward Clinical Application in Oncology. [PDF]

open access: yesCancer Control, 2023
Maqsood Q   +6 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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