Results 181 to 190 of about 26,078,541 (291)

Asciminib and inotuzumab ozogamicin: a new combination for highly refractory Ph-positive B-cell acute lymphoblastic leukemia. [PDF]

Leuk Res Rep
Strumilowska A, Devitt K, Conant J, Gardner JA, Volaric A, Hegde N, Adrianzen-Herrera D.   +6 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Bertieraacutiflora (Rubiaceae, Bertiereae), a new combination based on the overlooked Psychotriaacutiflora. [PDF]

PhytoKeys
Berger A.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Effects of a New Combination of Antibiofilm Enzymes, Antiadhesive Agents, and Liquorice Extracts on Plaque Accumulation in Dogs: An Unicenter, Controlled, and Randomized Study. [PDF]

J Vet Dent
Gawor JP, Ziemann D, Jank M, Gard C, Navarro C, Jahier B.   +5 more
europepmc   +1 more source

Intrapulmonary distribution of blood flow during exercise in pulmonary hypertension assessed by a new combination technique. [PDF]

Front Cardiovasc Med, 2023
Farina S, Pezzuto B, Vignati C, Laveneziana P, Agostoni P.   +4 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

<i>Sinosasadamingshanensis</i> (Poaceae, Bambusoideae), a new combination supported by morphological and molecular evidence. [PDF]

PhytoKeys
Zhang YT, Lin SY, Niu ZY, Jiang WX, Xia NH, Ding YL.   +5 more
europepmc   +1 more source

New species, a new combination, and DNA barcodes of Parachironomus Lenz, 1921 (Diptera, Chironomidae). [PDF]

Zookeys, 2023
Liu WB, Wang Y, Zhao KZ, Wang CY, Zhang JY, Yan CC, Lin XL.   +6 more
europepmc   +1 more source

Taxonomical notes on Torymidae (Insecta: Hymenoptera: Chalcidoidea)

Open Life Sciences, 2010
Stojanova Anelia
doaj   +1 more source