Results 141 to 150 of about 2,734,684 (304)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
New Combinations in the Florida Flora
New combinations are made for the following species and varieties within the flora of Florida: Agaloma oerstediana, Agaloma pubentissima, Aristida stricta var. beyrichiana, Asimina spatulata, Deeringothamnus rugelii var. pulchellus, Erianthus brevibarbis var. contortus, Ludwigia curtissii var. simpsonii, Nyssa biflora var. ursina, Pentalinon luteum var.
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
NEW COMBINATIONS IN THE LICHEN GENUS PARMOTREMA-SPP NEW-COMBINATION
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +2 more sources
A New Combination in Tabernaemontana (Apocynaceae)
In preparation of the Stemmadenia and Tabernaemontana (Apocynaceae) treatments for the upcoming Flora of the Venezuelan Guayana, the following new combination is required.
openaire +3 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Cinco especies de Terpsichorez A.R. Sm. son combinadas aquí en el reciente género Alansmia M. Kessler, Moguel, Sundue et Labiak: A. acrosora (A. Rojas) A. Rojas, A. cocosensis (A. Rojas) A. Rojas, A. esquiveliana (A. Rojas) A. Rojas, A. fabispora (Copel.)
Alexander F. Rojas-Alvarado
doaj
A New Combination in Erythrina (Leguminosae)
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +3 more sources

