Results 151 to 160 of about 19,529,676 (299)

New Jersey Pinelands Commission Monthly Management Reports

open access: yes, 2018
1st Qtr is only 2018 issue currently available.
New Jersey Pinelands Commission
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

New Jersey Pinelands Commission Monthly Management Reports

open access: yes, 2014
4th Quarter 2014.
New Jersey Pinelands Commission
core   +1 more source

NEW COMBINATIONS IN THE LICHEN GENUS PSEUDOPARMELIA-SPP NEW-COMBINATION

open access: yes, 1974
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

EL GENERO JARAVA RUIZ ET PAV. (STIPEAE-POACEAE): DELIMITACION Y NUEVAS COMBINACIONES THE GENUS JARAVA RUIZ ET PAV. (STIPEAE-POACEAE): DELIMITATION AND NEW COMBINATIONS

open access: yesGayana: Botanica, 2002
Se reconoce para América del Sur el género Jarava Ruiz et Pav. Este género incluiría a todas aquellas especies tratadas frecuentemente por los agrostólogos sudamericanos dentro de Stipa L. s.l. cuyos antecios presentan rasgos morfológicos asociados a una
Patricio Peñailillo
doaj  

NEW COMBINATIONS [PDF]

open access: yesChemical & Engineering News Archive, 2006
openaire   +1 more source

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