Results 251 to 260 of about 13,531 (288)

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

open access: yesAdvanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan   +21 more
wiley   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

open access: yesAdvanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Synthetic developmental biology: New tools to deconstruct and rebuild developmental systems

Seminars in Cell & Developmental Biology, 2023
Technological advances have driven many recent advances in developmental biology. Light sheet imaging can reveal single-cell dynamics in living three-dimensional tissues, whereas single-cell genomic methods open the door to a complete catalogue of cell types and gene expression states.
McNamara, H.   +2 more
openaire   +3 more sources

A New Theoretical Framework: New Developmentalism

Challenge, 2020
New Developmentalism is a theoretical framework being defined since the early 2000s searching to understand why most middle-income countries are falling behind the East Asian ones.
openaire   +1 more source

NEW TRENDS IN DEVELOPMENTAL PSYCHOLOGY*

British Journal of Educational Psychology, 1970
S ummary . W hat I would like to do is to consider the strategy of research in pre‐school education, and to make a plea to developmental and educational psychologists to take more ...
openaire   +2 more sources

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