Results 81 to 90 of about 17,089 (357)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Transforming the developmental welfare states in East Asia [PDF]
This article attempts to explain changes and continuity in the developmental welfare states in Korea and Taiwan Province of China (hereafter Taiwan) within the East Asian context. It first elaborates two strands of welfare developmentalism (selective vs.
Huck-ju Kwon
core
Shares of the Great War Effort: Brazil’s Returns from the Second World War [PDF]
, 2015 The first half of the twentieth century was a period so fraught with politi-cal, military, and economic tumult that it is easy to see why several of the world’s most powerful (and some not so powerful) nations turned to totalitarian forms of governance ...
Tyktor, Jon
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Preparation and developmental protocol for new biofilms process for protection quality, phytochemicals and taste compounds of apple ingredients during storage period through advanced methods as natural resources for future chemical and food industry of green technologies future [PDF]
, 2022 Waseem Ahmed
openalex +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
O novo desenvolvimentismo: limites e possibilidades frente ao debate atual
Cadernos de Campo, 2019 The new developmental theory is still under construction. However, there are already critiques elaborated by other hegemonic currents of economic thought in Brazil, both orthodox and heterodox.
Rafael de Azevedo Ramires Leão +1 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
From old to new developmentalism in latin America [PDF]
The failure of the Washington Consensus and of macroeconomic policies based onhigh interest rates and non-competitive exchange rates to generate economic growthprompted Latin America to formulate national development strategies. Newdevelopmentalism is an
Pereira, Luiz Carlos Bresser
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source