Results 141 to 150 of about 2,585,786 (243)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Group of leaders at United Jewish Appeal of Greater New York Women's Division Opening Rally

open access: yes, 1955
Digital ImageDigital finding ...
United Jewish Appeal of Greater New York   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Hyperinflated lungs compress the heart during expiration in COPD patients: a new finding on dynamic-ventilation computed tomography. [PDF]

open access: yesInt J Chron Obstruct Pulmon Dis, 2017
Xu Y   +7 more
europepmc   +1 more source

Children returning from vacation to the Jewish Child Care Association of New York

open access: yes, 1938
Digital ImageDigital finding ...
Federation of Jewish Philanthropies of New York   +1 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Basilar artery aneurysm: a new finding in classic infantile Pompe disease. [PDF]

open access: yesMuscle Nerve, 2013
Patel TT   +5 more
europepmc   +1 more source

Board of Trustees, Special Meeting, October 10, 1985

open access: yes, 1985
Special meeting on the merger between United Jewish Appeal of Greater New York and Federation of Jewish Philanthropies of New York, including updates on the merger negotiations from Daniel S.
Federation of Jewish Philanthropies of New York
core  

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