Results 141 to 150 of about 7,588,880 (317)

Living and Learning with New Media: Summary of Findings from the Digital Youth Project [PDF]

, 2009
Ito, Mizuko, Horst, Heather A., Bittanti, Matteo, Boyd, Danah, Herr-Stephenson, Becky, Lange, Patricia G., Pascoe, C. J., Robinson, Laura   +7 more
openalex   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Retro-maxillary nasal recess: a case report with a new finding

The Egyptian Journal of Otolaryngology
Background Retro-maxillary recess of the nasal cavity is an area that has not yet described in the literature. Objective To report, present, and describe a previously non-reported case which has bilateral retro-maxillary nasal recess by multi-slices ...
Mohammad Waheed El-Anwar
doaj   +1 more source

Finding a New Identity

Journal of the Korean Academy of Child and Adolescent Psychiatry, 2020
openaire   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Finding New VEGFR2 Inhibitors Using Support Vector Machine Classification Model [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: In our current era, the prevalence of cancer and its associated mortality rates have become a pressing concern. As such, finding effective methods for treating cancer has become a matter of significant importance.
Nooshin Arabi, Mohammad Reza Torabi, Afshin Fassihi, Fahimeh Ghasemi   +3 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Cerebral defects and nephrogenic diabetes insipidus with the ARC syndrome: Additional findings or a new syndrome (ARCC-NDI)? [PDF]

, 1997
Rosalind Coleman, Johan L.K. Van Hove, C. Richard Morris, J. Marc Rhoads, Marshall Summar   +4 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Extremal extensions of entanglement witnesses: Finding new bound entangled states [PDF]

, 2011
Ritabrata Sengupta, Arvind Arvind
openalex   +1 more source