Results 161 to 170 of about 21,961,066 (284)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

New finding on a migratory bird, the fowl tick Argas (Persicargas) persicus (Oken, 1818), in Italy. [PDF]

Exp Appl Acarol
Menegon M, Casale F, Mancuso E, Di Luca M, Severini F, Monaco F, Toma L.   +6 more
europepmc   +1 more source

Cerebral Edema in Chronic Mountain Sickness: a New Finding. [PDF]

Sci Rep, 2017
Bao H, Wang D, Zhao X, Wu Y, Yin G, Meng L, Wang F, Ma L, Hackett P, Ge RL.   +9 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Is there a new finding added to the fibromyalgia syndrome? [PDF]

North Clin Istanb, 2014
Sarifakioglu B, Guzelant AY, Alpsoy S, Topcu B, Unsal C, Sahin N.   +5 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Giant seborrheic keratosis with a new dermoscopic finding

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2015
Geethu Francis Alapatt, Ramesh M Bhat, Sukumar Dandekeri, Meryl Sonia Rebello   +3 more
doaj   +1 more source

"Juggling" Behavior in Wild Hainan Gibbons, a New Finding in Nonhuman Primates. [PDF]

Sci Rep, 2016
Deng H, Zhou J.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Throwing Light onto the Core of a Halo Nevus: A New Finding. [PDF]

Indian J Dermatol, 2016
Babu A, Bhat MR, Dandeli S, Ali NM.
europepmc   +1 more source