Results 61 to 70 of about 67,835 (263)
Searching for a new light gauge boson with axial couplings in muon beam dump experiments
We present a formalism for new U(1) interactions involving weak hypercharge, baryon, and lepton numbers, and a possible axial symmetry generator F A in the presence of a second Brout-Englert-Higgs doublet.
Pierre Fayet, María Olalla Olea-Romacho
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Systematically testing singlet models for (g − 2) μ
We comprehensively study all viable new-physics scenarios that resolve the muon (g − 2) μ anomaly with only Standard Model singlet particles coupled to muons via renormalizable interactions. Since such models are only viable in the MeV–TeV mass range and
Rodolfo Capdevilla +3 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A realistic theory of E6 unification through novel intermediate symmetries
We propose a non-supersymmetric E6 GUT with the scalar sector consisting of 650 ⨁ 351′ ⨁ 27. Making use of the first representation for the initial symmetry breaking to an intermediate stage, and the latter two representations for second-stage breaking ...
K. S. Babu, Borut Bajc, Vasja Susič
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Multi-lepton jets from quadruple Z′ via the Higgs decay at LHC
We investigate multi-lepton jet events from the decay of the 125 GeV Higgs boson (h) into quadruple new gauge bosons (Z′) at the LHC. Such an exotic decay is realized via the process of h → ϕϕ → Z′Z′Z′Z′ with new scalar boson ϕ in models with an ...
Jinmian Li, Takaaki Nomura, Kei Yagyu
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
New N=2 supersymmetric gauge theories: The double tensor multiplet and its interactions
The double tensor multiplet of D=4, N=2 supersymmetry, relevant to type IIB superstring vacua, is derived and its gauge invariant and N=2 supersymmetric interactions are analysed, both self-interactions and interactions with vector multiplets and hypermultiplets.
openaire +3 more sources

