Results 61 to 70 of about 515,250 (294)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Anomalous gauge-boson couplings and the Higgs-boson mass

open access: yes, 2004
We study anomalous gauge-boson couplings induced by a locally SU(2) x U(1) invariant effective Lagrangian containing ten operators of dimension six built from the boson fields of the Standard Model (SM) before spontaneous symmetry breaking (SSB).
Altarelli   +29 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Tri-hypercharge: a separate gauged weak hypercharge for each fermion family as the origin of flavour

open access: yesJournal of High Energy Physics, 2023
We propose a tri-hypercharge (TH) extension of the Standard Model (SM) in which a separate gauged weak hypercharge is associated with each fermion family.
Mario Fernández Navarro   +1 more
doaj   +1 more source

An Approach to Higher Dimensional Theories Based on Lattice Gauge Theory

open access: yes, 2003
A higher dimensional lattice space can be decomposed into a number of four-dimensional lattices called as layers. The higher dimensional gauge theory on the lattice can be interpreted as four-dimensional gauge theories on the multi-layer with ...
Creutz   +8 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Higgs Mechanism for Vector Galileons [PDF]

open access: yes, 2015
Vector theories with non-linear derivative self-interactions that break gauge symmetries have been shown to have interesting cosmological applications.
Hull, Matthew   +2 more
core   +2 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Grand Color axion

open access: yesJournal of High Energy Physics, 2022
We present a model that solves the strong CP problem via an axion parametrically heavier than the standard one. Within this picture the Standard Model quarks are embedded into a larger non-abelian Grand Color group that at high scales splits into ...
Alessandro Valenti   +2 more
doaj   +1 more source

Composite Quarks and Leptons from Dynamical Supersymmetry Breaking without Messengers [PDF]

open access: yes, 1997
We present new theories of dynamical SUSY breaking in which the strong interactions that break SUSY also give rise to composite quarks and leptons with naturally small Yukawa couplings.
A. Chamseddine   +55 more
core   +2 more sources

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