Results 41 to 50 of about 3,377 (211)

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

The effect of Trichoderma on the growth and development of tomato and bean under greenhouse and field conditions

Annals of Tropical Research, 2018
Trichoderma’s plant growth stimulating effect is well-recognized besides its well-known role as a biocontrol agent against plant diseases. Two greenhouse and field studies were conducted at the Papua New Guinea University of Technology (PNGUOT) to test ...
Gwendolyn Ban, Shamsul Akanda, Macquin Maino   +2 more
doaj   +1 more source

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

Advanced Science, EarlyView.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou, Tobias Winkler, Bin Chen, Marta Grzeski, Yilong Yang, Florian N. Fleckenstein, Dominik Geisel, Alexander Hildebrandt, Daniela Aschenbrenner, Marie Agatha Mohn, Benjamin Claass, January Weiner 3rd, Sven Geissler, Georg N. Duda, Søren P. Sheikh, Oliver Klein, Tazio Maleitzke   +16 more
wiley   +1 more source

New Guinea

, 2013
New Guinea is the world s second biggest non-continental island; only Greenland is larger. Politically, the island is divided in two. The western half, generally referred to outside Indonesia as West Papua , comprises the two Indonesian provinces of Papua and West Papua; the eastern half is the independent country of Papua New Guinea (PNG).
May, Ronald, Matbob, Patrick, Papoutsaki, Evangelia   +2 more
openaire   +2 more sources

The effects of COVID-19 on maternal, newborn and child health services in Papua New Guinea

Global Public Health
Papua New Guinea’s health system faces ongoing challenges in the provision of maternal and child health and has some of the poorest health indicators in the world.
Lisa M. Vallely, Jamee Newland, Nalisa Neuendorf, Agnes Kupul Mek, Rachael Farquhar, Zebedee Kerry, Ruthy Boli-Neo, Mikaela Seymour, Melanie Wratten, Herick Aeno, Richard Nake Trumb, Anna Maalsen, Caroline SE Homer, Angela Kelly-Hanku   +13 more
doaj   +1 more source

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Using multilayer socioecological networks to assess ecosystem service flow in a subsistence farming community in Papua New Guinea

People and Nature
Ecosystem services are rapidly degrading under anthropogenic pressure. Therefore, it is increasingly important to understand how ecosystem services flow, particularly at local scales, where people directly rely on nature for their livelihoods and well ...
Anna Stanworth, Kiole Imale, Brus Isua, Anne M. Anji, Francesca F. Dem, Vojtech Novotný, Harry E. R. Shepherd, Kelvin S.‐H. Peh, Rebecca J. Morris   +8 more
doaj   +1 more source

Acceptability of self-collected vaginal swabs and point-of-care testing for sexually transmitted and genital infections among pregnant women in Papua New Guinea

Global Public Health
The self-collection of vaginal swabs and point-of-care testing and treatment of sexually transmitted infections (STIs) is reported from several low-and middle-income countries. However, the reporting on women’s experiences of self-collection and same-day
Lisa M. Vallely, Priscilla Poga, Michaela A. Riddell, Handan Wand, Alice Mengi, Steven G. Badman, John Bolnga, Delly Babona, William S. Pomat, Somu Nosi, Andrew J. Vallely, Angela Kelly-Hanku   +11 more
doaj   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source