Results 51 to 60 of about 663,666 (301)

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, EarlyView.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

One size does not fit all: HIV prevalence and correlates of risk for men who have sex with men, transgender women in multiple cities in Papua New Guinea

BMC Public Health, 2019
Background Biobehavioral data about men who have sex with men (MSM) and transgender women (TGW) in Papua New Guinea (PNG) are limited to those who sell sex.
Avi J. Hakim, Kelsey Coy, Steven G. Badman, Barne Willie, Rebecca Narokobi, Josephine Gabuzzi, Simon Pekon, Martha Kupul, Parker Hou, Herick Aeno, Ruthy Neo Boli, Joshua Nembari, Sophie Ase, Angelyne Amos, Nick Dala, Damian Weikum, Steven Callens, John M. Kaldor, Andrew J. Vallely, Angela Kelly-Hanku, on behalf of the Kauntim mi tu Study Team   +20 more
doaj   +1 more source

Measuring Wasting and Stunting Prevalence Among Children Under 5 Years of Age and Associated Risk Factors in Papua New Guinea: New Evidence From the Comprehensive Health and Epidemiological Surveillance System

Frontiers in Nutrition, 2021
Background: Papua New Guinea (PNG) has undergone a significant health transition, with the prevalence of non-communicable diseases increasing. Many children under 5 years of age suffer from the burden of malnutrition.
Bang Nguyen Pham, Vinson D. Silas, Anthony D. Okely, William Pomat   +3 more
doaj   +1 more source

Breaking away from the land policy stalemate [PDF]

, 2015
Unlocking the potential of land is crucial for realising the development aspirations of the people of Papua New Guinea and the island nations of the Pacific, yet land policy development has largely been absent in these countries. Land is a political ‘hot
Levantis, Theo, Yala, Charles
core  

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

New species or interesting records of foliicolous lichens : 7., Calenia flava (Ostropales: Gomphillaceae) [PDF]

, 2000
Calenia flava spec. nova from Papua New Guinea is described and illustrated. The new species is closely related to C. phyllogena but differs in the larger apothecia with yellow disc and the abundance of sterile thallus ...
Lücking, Robert, Sipman, Harrie J. M., Sérusiaux, Emmanuël   +2 more
core  

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

Advanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina, Kanghwan Kim, Wesley Charles Smith, Keuntae Kim, Shinwoo Lee, Jiwan Woo, Il‐Joo Cho   +6 more
wiley   +1 more source

Risk factors and pregnancy outcomes associated with placental malaria in a prospective cohort of Papua New Guinean women

Malaria Journal, 2017
Background Plasmodium falciparum in pregnancy results in substantial poor health outcomes for both mother and child, particularly in young, primigravid mothers who are at greatest risk of placental malaria (PM) infection.
Elvin Lufele, Alexandra Umbers, Jaume Ordi, Maria Ome-Kaius, Regina Wangnapi, Holger Unger, Nandao Tarongka, Peter Siba, Ivo Mueller, Leanne Robinson, Stephen Rogerson   +10 more
doaj   +1 more source

Media And Government Relations In Papua New Guinea [PDF]

, 2006
All is not well with news media in Papua New Guinea. Media and government relations are stressed, a situation adverse to the country's development. Media organisations have to deal with operational difficulties, threats against editorial freedom, and ...
Duffield, Lee
core   +1 more source