Results 71 to 80 of about 693,317 (349)

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

Insufficient duration of insecticidal efficacy of Yahe® insecticide-treated nets in Papua New Guinea

open access: yesMalaria Journal
Background Insecticide-treated nets (ITNs) are the backbone of anti-malarial vector control in Papua New Guinea (PNG). Over recent years the quality and performance of ITNs delivered to PNG decreased, which has likely contributed to the stagnation in the
Nakei Bubun   +8 more
doaj   +1 more source

Effects of Meloidogyne incognita on the Yield and Quality of Sweet Potato in the Humid Lowlands of Papua New Guinea

open access: yesAnnals of Tropical Research, 2015
Field experiments were conducted in 2012 and 2013 to study the effects of inoculum densities of Meloidogyne incognita applied at 10, 100, 1000, 5000, and 10000 juveniles/eggs per 500 cm3 along with un- inoculated control treatments, on a susceptible ...
Macquin K. Maino, Shamsul Akanda
doaj   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Continuous quality improvement in a community-wide TB screening and prevention programme in Papua New Guinea

open access: yesPublic Health Action
SETTING: Daru Island in Papua New Guinea (PNG) has a high prevalence of TB and multidrug-resistant TB (MDR-TB). OBJECTIVE: To evaluate the early implementation of a community-wide project to detect and treat TB disease and infection, outline the decision-
N.P. Pank   +27 more
doaj   +1 more source

Polynomial interpolation methods in development of local geoid model

open access: yesEgyptian Journal of Remote Sensing and Space Sciences, 2018
In geodesy three surfaces, the physical surface of the earth, the geoid and the reference ellipsoid are encountered giving rise to orthometric height (h), the ellipsoidal height (H) and the geoidal separation (N).
Rabindra Kumar Das   +3 more
doaj   +1 more source

Global Diversification Rates of Ferns Across Spatial and Climatic Gradients

open access: yesAdvanced Science, EarlyView.
Diversification rates of fern genera across the phylogeny. Abstract Geographic patterns of diversity in any group of plants are the result of the interplay of environmental conditions and the evolutionary dynamics of the respective plant group. Here, the geographic distribution of current mean diversification rates (MDR) is explored at the genus level ...
Hong Qian, Michael Kessler, Shenhua Qian
wiley   +1 more source

Impatiens x New Guinea Hybrids New Guinea Impatiens

open access: yesEDIS, 2007
This document provides an overview of the New Guinea impatiens, a versatile and colorful annual plant. It highlights the plant’s distinguishing features, including its brilliantly marked foliage, large single flowers in various colors, and its ability to tolerate greater amounts of sun once established.
Edward Gilman, Teresa Howe
openaire   +5 more sources

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo   +16 more
wiley   +1 more source

New bryophyte taxon records for tropical countries 2 [PDF]

open access: yes, 1998
Norris & T. Kop. Sabah, Mt. Kinabalu, Mary Strong Clemens. 10741, 15.11.1915 (L) as „Campylopus metzlerioides Broth. nom. nud.“ The species was known before (mostly as Atractylocarpus comosus Dix.) from Sumatra, Celebes, New Guinea, Bhutan and Nepal [JPF]
Eggers, Jens   +2 more
core  

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