Results 71 to 80 of about 126,433 (311)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Sploty

Teksty Drugie, 2017
Czapliński presents new research in the humanities of the last decade, identifying general deficiencies (mostly methodological ones) and general functions (the intertwining of researcher and subject, of the humanities with science, of science with ...
Przemysław Czapliński
doaj  

A New Way of Teaching Humanities in Medical School: Critical Medical Humanities

Journal of Medical Education and Curricular Development
Purpose This study investigates medical students’ experiences with a pre-clerkship critical medical humanities (CMH) curriculum that emphasized power, privilege, and inequities in healthcare. Methods Twenty-six third-year medical students at a semi-rural
Rebecca L. Volpe, Nancy E. Adams, Britta M. Thompson, Jocelyn Simmers, Sonia Chen, Bernice L. Hausman   +5 more
doaj   +1 more source

Agilität, Versionierung und Open Source. Softwareentwicklung und Praktiken der Geisteswissenschaften

Zeitschrift für digitale Geisteswissenschaften, 2018
The Digital Humanities open up the possibility to access literary and historical sources in new ways. They enable the large-scale data analysis of cultural artifacts, which can be understood as the ...
Arndt Niebisch
doaj   +1 more source

Disciplined: Using educational studies to analyse 'Humanities Computing'

, 2006
Humanities Computing is an emergent field. The activities described as 'Humanities Computing' continue to expand in number and sophistication, yet no concrete definition of the field exists, and there are few academic departments that specialize in this ...
Terras, M
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Methods for Extracting Relational Data from Unstructured Texts Prior to Network Visualization in Humanities Research

Journal of Open Humanities Data, 2020
Network modelling methodologies in the digital humanities have been be used to advance inquiry in a variety of areas—most commonly those having to do with correspondence, citation, and social media networks.
S. Scott Graham, Zoltan P. Majdik, Dave Clark   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Humanities Unbound: Supporting Careers and Scholarship Beyond the Tenure Track [PDF]

, 2015
As humanities scholars increasingly recognize the value of public engagement, and as the proportion of tenure-track faculty positions available continues to decline, many humanities programs are focusing renewed attention on equipping graduate students ...
Katina Rogers, Rogers, Katina
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source