Results 41 to 50 of about 24,171,676 (198)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Refined carbohydrates and the overfat pandemic: implications for brain health and public health policy

open access: yesFrontiers in Public Health
Refined carbohydrate exposure—principally added sugars and rapidly digestible starches—is a modifiable driver of the overfat pandemic and carries downstream risks for brain health.
Philip Maffetone, Paul B. Laursen
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Voting for a democratic South Africa needs an independent authority to put it all together [PDF]

open access: yes, 1994
462.B.2.3(17).pdf created from the media publications in the SA Election material Collection MS 462, held in the Manuscripts Section of the Stellenbosch Library and Information Service.Voting for a democratic South Africa needs an independent authority ...

core   +1 more source

Foster Youth: HHS Actions Could Improve Coordination of Services and Monitoring of States' Independent Living Programs [PDF]

open access: yes, 2004
A letter report issued by the Government Accountability Office with an abstract that begins "To improve outcomes for youth leaving foster care, Congress passed the Foster Care Independence Act of 1999 (FCIA), which increased the allocation of federal ...
United States. Government Accountability Office.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

FUNIPAMO - Telegram message to the Heads of African Independent States and Prime Ministers, 1963 May 22

open access: yes, 1963
Telegram declaring UDENAMO, MANU and MANCU dissolution from FRELIMO and formation of FUNIPAMO. The message also ask the Heads of African Independent States and Prime Ministers for financial aids, arms, and ...
Frente Unida Anti-imperialista de Moçambique (FUNIPAMO)
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy