Results 71 to 80 of about 24,171,676 (198)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
When safety for you means danger for me: the racial politics of carceral public safety discourse
Safety is a human right and universal need, and yet we as researchers and practitioners often take for granted the conditions that help people feel safe.
Verónica Caridad Rabelo +3 more
doaj +1 more source
"Briefing book for the Garden State Parkway" / New Jersey Highway Authority: 42 p.
New Jersey. Legislature. General Assembly. Independent and Regional Authorities Committee
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Farmers' bulletin (United States. Dept. of Agriculture)
Discusses Arbor Day as a holiday that recognizes the importance of United States forests and discusses a citizen's duty to preserve them and foster new growth of ...
United States. Forest Service. +1 more
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Map of the newly independent states showing final assembly plants, production facilities, international boundaries, water features and major cities.; "727015 (R00781) 1-93."; On accompanying title sheet and booklet: OSE 93-10001, January 1993.; At head ...
United States. Central Intelligence Agency. Directorate of Intelligence.
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Whole genome sequence of a long-legged fly Condylostylus longicornis from Hawaiʻi
Bogdan Sieriebriennikov +9 more
doaj +1 more source

