Results 151 to 160 of about 636,540 (259)

The Prevalence and Correlates of Child Sexual Offending Behaviours and Attitudes Among Men in Australia, the United Kingdom, and the United States: Study Methodology. [PDF]

J Interpers Violence
Whitten T, Salter M, Woodlock D.
europepmc   +1 more source

Machine‐Learning Decomposition Identifies a Big Two Structure in Human Personality with Distinct Neurocognitive Profiles

Advanced Science, EarlyView.
Using machine learning on a mega‐scale global dataset (n = 1,336,840) reveals a robust personality trait architecture beyond the Big Five. A Big Two model, broadly capturing social engagement and internal mentation, defines a geometric space that links personality to neurocognitive profiles.
Kaixiang Zhuang, Ji Chen, Jinfeng Han, Wei Cheng, Jiang Qiu, Jianfeng Feng, Simon Eickhoff, Deniz Vatansever   +7 more
wiley   +1 more source

Vaccine preferences and their role for vaccine confidence and uptake: a meta-ethnography. [PDF]

Glob Health Action
Landicho J, Bravo TA, Wachinger J, Silvestre C, Bärnighausen K, Scott K, Bärnighausen T, McMahon SA, Reñosa MDC.   +8 more
europepmc   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

A GP drop-in clinic model providing holistic community care in family hubs: Service evaluation findings and next steps. [PDF]

Public Health Pract (Oxf)
Macnamara A, Witney J, Christmas H, Nudrat S, Morton K, Blower S.   +5 more
europepmc   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source

Person-Centered Multimorbidity Care in UK Primary Care: Identifying Changes to Practice. [PDF]

Ann Fam Med
Megson M, Hilton A, Aryankhesal A, Blake J, Killett A, van Horik J, Fox C, Reeve J.   +7 more
europepmc   +1 more source

Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

Advanced Science, EarlyView.
This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu, Kexing Li, Yuge Wang, Hongyu Li, Hongyu Zhao   +4 more
wiley   +1 more source

Characteristics associated with frequent sexually transmitted infection (STI) testing in a community-based sample of gay, bisexual, and other men who have sex with men (GBMSM), United Kingdom, 2024. [PDF]

PLOS Glob Public Health
Findlater L, Baldry G, Harb AK, Mullen D, Phillips D, Buitendam E, Lowndes CM, Reid D, Mercer CH, Saunders J, Ogaz D, Mohammed H.   +11 more
europepmc   +1 more source