Results 171 to 180 of about 636,540 (259)

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

The impact of emerging technologies on education, roles and career progression of radiation therapists: a delphi consensus based on the ESTRO RTT workshop. [PDF]

Tech Innov Patient Support Radiat Oncol
Buijs M, Sousa F, Couto J, Bossa P, Clarkson M, Devereux T, Domingues DR, Harrison L, Kim T, Leung VW, Ochandorena K, Rolo L, Shepherd M, Siddiqi F, Strikou D, Tong E, Weerd EV, Williamson A, Wojcikowski S, Simões R.   +19 more
europepmc   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Dual mechanism of anti-seizure medications in controlling seizure activity. [PDF]

Brain Commun
Besné GM, Molefi E, Smith B, Evans N, Gascoigne SJ, Thornton C, Chowdhury FA, Diehl B, Duncan JS, McEvoy AW, Miserocchi A, de Tisi J, Walker MC, Taylor PN, Wang Y.   +14 more
europepmc   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Scaling up efforts to target evolving viruses. [PDF]

Elife
Wang L, Salje H.
europepmc   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

Advanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka, Richard T. Osgood, Hidetomi Nitta, Artur A. Indzhykulian   +3 more
wiley   +1 more source

Implementing AI innovation in radiology departments in the English NHS: a qualitative study on the experiences of professionals, patient groups and innovators. [PDF]

Front Digit Health
Stavropoulou C, Scarbrough H, Rawlinson J, Cui M, Baldwin D, Woznitza N.   +5 more
europepmc   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

AlphaFold Protein Structure Database 2025: a redesigned interface and updated structural coverage. [PDF]

Nucleic Acids Res
Bertoni D, Tsenkov M, Magana P, Nair S, Pidruchna I, Querino Lima Afonso M, Midlik A, Paramval U, Lawal D, Tanweer A, Last M, Patel R, Laydon A, Lasecki D, Dietrich N, Tomlinson H, Žídek A, Green T, Kovalevskiy O, Lau A, Kandathil S, Bordin N, Sillitoe I, Mirdita M, Jones D, Orengo C, Steinegger M, Fleming JR, Velankar S.   +28 more
europepmc   +1 more source