Results 61 to 70 of about 2,631,173 (308)

Look-up Tables to Link 1991 Population Statistics to the 1998 Local Government Areas [PDF]

open access: yes, 1998
Between 1995 and 1998 the local authority structure and geography of the United Kingdom was substantially revised. The two-tier system of local government was abolished in Wales, Scotland, and in parts of non-metropolitan England, and replaced with a ...
Rees, P., Wilson, T.
core  

Comparing research investment to United Kingdom institutions and published outputs for tuberculosis, HIV and malaria: A systematic analysis across 1997-2013 [PDF]

open access: yes, 2015
Background: The "Unfinished Agenda" of infectious diseases is of great importance to policymakers and research funding agencies that require ongoing research evidence on their effective management.
A Aghaei Chadegani   +31 more
core   +7 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

The new micro-kingdoms of eukaryotes [PDF]

open access: yesBMC Biology, 2013
Early metagenetic surveys of micro-eukaryotic diversity revealed numerous phylotypes that seemed unrelated to any described eukaryotic taxa. It has been proposed that some of them may represent novel kingdom-level taxonomic diversity in eukaryotes. However, detailed analysis of DNA sequences retrieved from environmental samples and assigned to these ...
openaire   +3 more sources

Creativity and the experts: New Labour, think tanks, and the policy process [PDF]

open access: yes, 2009
This article explores the role of expertise in public debate on creative industries policy in the United Kingdom. The first section gives an overview of the emergence of expertise in government and the rise of think tanks, locating this within a wider ...
Schlesinger, P.
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Prolactin Monitoring for Inpatients on Antipsychotic Drugs: A Clinical Audit

open access: yesBJPsych Open
Aims Many antipsychotics are known to adversely affect prolactin levels causing hyperprolactinemia. National Institute for Health and Care Excellence (NICE) guidelines have suggested monitoring of prolactin levels.
Farida Kotait   +2 more
doaj   +1 more source

New New Deals: Reforming Welfare Again? [PDF]

open access: yes, 2010
In both the Unites States and the United Kingdom, the idea of the New Deal has proved a potent political symbol during this crisis. In what follows, I explore some of the ways in which the imagery of the New Deal has been deployed and consider some of ...
Clarke, John
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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