Results 121 to 130 of about 1,363,811 (301)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Dark showers from Z-dark Z′ mixing

Journal of High Energy Physics
We discuss dark shower signals at the LHC from a dark QCD sector, containing GeV-scale dark pions. The portal with the Standard Model is given by the mixing of the Z boson with a dark Z′ coupled to the dark quarks.
Hsin-Chia Cheng, Xu-Hui Jiang, Lingfeng Li, Ennio Salvioni   +3 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Direct deflection of Millicharged radiation

Journal of High Energy Physics
Millicharged particles are generic in theories of dark sectors. A cosmic or local abundance of them may be produced by the early universe, stellar environments, or the decay or annihilation of dark matter/dark energy.
Asher Berlin, Surjeet Rajendran, Harikrishnan Ramani, Erwin H. Tanin   +3 more
doaj   +1 more source

Investigation of magneto-optical properties of ferrofluids by laser light scattering techniques

, 2017
Investigation of magnetooptical characteristics of ferrofluids is an important task aimed at the development of novel optoelectronic systems. This article reports on the results obtained in the experimental studies of the factors that affect the ...
Kuzmin, Yu I, Nepomnyashchaya, E K, Pleshakov, I V, Prokofiev, A V, Velichko, E N   +4 more
core   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Low-energy supernova constraints on lepton flavor violating axions

Journal of High Energy Physics
The extreme conditions within the supernova core, a high-temperature and high-density environment, create an ideal laboratory for the search for new physics beyond the Standard Model.
Zi-Miao Huang, Zuowei Liu
doaj   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source

The Juno mission as a probe of long-range new physics

Journal of High Energy Physics
Orbits of celestial objects, especially the geocentric and heliocentric ones, have been well explored to constrain new long-range forces beyond the Standard Model (SM), often referred to as fifth forces.
Praniti Singh, Shi Yan, Itamar J. Allali, JiJi Fan, Lingfeng Li   +4 more
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source