Results 101 to 110 of about 1,363,811 (301)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Journal of High Energy PhysicsWe entertain the possibility that transient astrophysical sources can produce a flux of dark particles that induce ultra-high-energy signatures at neutrino telescopes such as IceCube and KM3NeT.
Yasaman Farzan, Matheus Hostert
doaj +1 more source
Transporting long-lived quantum spin coherence in a photonic crystal fiber
, 2019 Confining particles in hollow-core photonic crystal fibers has opened up new prospects to scale up the distance and time over which particles can be made to interact with light.
Chen, Zilong +3 more
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Ultra-directional super-scattering of homogenous spherical particles with radial anisotropy
, 2015 We study the light scattering of homogenous radially-anisotropic spherical particles. It is shown that radial anisotropy can be employed to tune effectively the electric resonances, and thus enable flexible overlapping of electric and magnetic dipoles of
Liu, Wei
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Explanation of the hints for a 95 GeV Higgs boson within a 2-Higgs Doublet Model
Journal of High Energy PhysicsWe suggest an explanation for and explore the consequences of the excess around 95 GeV in the di-photon and di-tau invariant mass distributions recently reported by the CMS collaboration at the Large Hadron Collider (LHC), together with the discrepancy ...
A. Belyaev +5 more
doaj +1 more source
Light millicharged particles and large scale cosmic magnetic fields
, 2014 After a brief review of different types of scenarios suggested for the solution of the problem of galactic and intergalactic magnetic field generation, the mechanism based on the electric current induction by hypothetical millicharged particles ...
Dolgov, A. D.
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source