Results 91 to 100 of about 380,831 (268)

Low-energy supernova constraints on lepton flavor violating axions

open access: yesJournal of High Energy Physics
The extreme conditions within the supernova core, a high-temperature and high-density environment, create an ideal laboratory for the search for new physics beyond the Standard Model.
Zi-Miao Huang, Zuowei Liu
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

The Juno mission as a probe of long-range new physics

open access: yesJournal of High Energy Physics
Orbits of celestial objects, especially the geocentric and heliocentric ones, have been well explored to constrain new long-range forces beyond the Standard Model (SM), often referred to as fifth forces.
Praniti Singh   +4 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Complete light long-lived particles searches in Type-I 2HDM

open access: yesJournal of High Energy Physics
Recently, the study of long-lived particles (LLPs) has attracted increasing attention. In this work, we analyze the full parameter space of the Type-I Two-Higgs-Doublet Model (2HDM) that allows for light long-lived scalar (H) and pseudoscalar (A ...
Xueying Qi, Huayang Song, Wei Su
doaj   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Angling for insights: illuminating light new physics at Mu3e through angular correlations

open access: yesJournal of High Energy Physics
We examine the capability of Mu3e to probe light new physics scenarios that produce a prompt electron-positron resonance and demonstrate how angular observables are instrumental in enhancing the experimental sensitivity. We systematically investigate the
Simon Knapen   +3 more
doaj   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

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