Results 91 to 100 of about 382,262 (315)
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
New Light Particle Searches with PADME
The PADME experiment at Laboratori Nationali di Frascati is designed to study possible dark matter explanations relying on the presence of a light particle that acts as a mediator between the visible and the hidden sectors. Three data-taking runs have resulted in the collection of more than \(10^{13}\) positrons-on-target.
openaire +1 more source
Search for new light particles at ILC main beam dump
7 pages, 5 figures.
Sakaki, Yasuhito, Ueda, Daiki
openaire +2 more sources
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Forces on a Rayleigh particle in the cover region of a planar waveguide
We report on the optimization of a waveguide structure for the maximization of the radiation forces exerted on a Rayleigh particle in the cover region.
Luff, B.J. +3 more
core +1 more source
Explanation of the hints for a 95 GeV Higgs boson within a 2-Higgs Doublet Model
We suggest an explanation for and explore the consequences of the excess around 95 GeV in the di-photon and di-tau invariant mass distributions recently reported by the CMS collaboration at the Large Hadron Collider (LHC), together with the discrepancy ...
A. Belyaev +5 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Stellar cooling bounds on new light particles: plasma mixing effects [PDF]
Strong constraints on the coupling of new light particles to the Standard Model (SM) arise from their production in the hot cores of stars, and the effects of this on stellar cooling.
Hardy, Edward +3 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Off-axis transmission holographic system for recording aquatic particles
We describe a holographic system for recording particles suspended in water. The hologram plate is located in air, separated from the test tank by an air/glass/water boundary. The holographic emulsion is therefore unaffected by adverse aquatic conditions
Lampitt, RS +4 more
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