Results 71 to 80 of about 1,363,811 (301)

Baryonic dark forces in electron-beam fixed-target experiments

Journal of High Energy Physics
New GeV-scale dark forces coupling predominantly to quarks offer novel signatures that can be produced directly and searched for at high-luminosity colliders. We compute the photon-proton and electron-proton cross sections for producing a GeV-scale gauge
Safa Ben Othman, Armita Jalooli, Sean Tulin   +2 more
doaj   +1 more source

Keeping it simple: simplified frameworks for long-lived particles at neutrino facilities

Journal of High Energy Physics, 2023
Modern-day accelerator neutrino facilities are excellent venues for searches for new-physics particles. Many distinct new-physics models predict overlapping signatures and phenomenology in these experiments.
Brian Batell, Wenjie Huang, Kevin J. Kelly   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Constraints on photon mass and dark photon from the Jovian magnetic field

Journal of High Energy Physics
The Jovian magnetic field, being the strongest and largest planetary one in the solar system, could offer us new insights into possible microscopic scale new physics, such as a non-zero mass of the Standard Model (SM) photon or a light dark photon ...
Shi Yan, Lingfeng Li, JiJi Fan
doaj   +1 more source

LEX-EFT: the Light Exotics Effective Field Theory

Journal of High Energy Physics, 2023
We propose the creation of a Light Exotics Effective Field Theory (LEX-EFT) catalog. LEX-EFT is a generic framework to capture all interactions between the Standard Model (SM) and all (or at least a large class of) theoretically allowed exotic states ...
Linda M. Carpenter, Taylor Murphy, Matthew J. Smylie   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Lienard-Wiechert field of accelerated massless charges

, 2012
We determine for the first time the electromagnetic field generated by a generic massless accelerated charge, solving exactly Maxwell's equations. This result may shed new light on the possible existence of such particles in nature.Comment: 9 pages, no ...
Azzurli, Francesco, Lechner, Kurt
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Quark-universal U(1) breaking scalar at the LHC

Journal of High Energy Physics
If the quarks or leptons are charged under a new U(1) gauge symmetry, then besides a Z′ boson there must exist at least one new boson whose decay products include Standard Model particles. In the case of a minimal symmetry breaking sector, that new boson
Lorin Armbruster, Bogdan A. Dobrescu, Felix Yu   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source