Results 51 to 60 of about 1,760,261 (267)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

RETRACTED ARTICLE: The interrelationships between Chinese learners’ trait emotional intelligence and teachers’ emotional support in learners’ engagement

BMC Psychology
Background One noteworthy concern within the realm of education is the level of engagement demonstrated by students. Among the factor that can have a crucial role in this domain is teacher support, especially emotional support which has an impact on ...
Yao Yan, Xusheng Zhang, Tong Lei, Pei Zheng, Chao Jiang   +4 more
doaj   +1 more source

Advancing Interior Design with AI: Controllable Stable Diffusion for Panoramic Image Generation

Buildings
AI-driven technologies have significantly advanced panoramic image generation in interior design; however, existing methods often lack controllability and consistency in rendering high-quality, coherent panoramas.
Wanggong Yang, Congcong Wang, Luxiang Liu, Shuying Dong, Yifei Zhao   +4 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Best Version of Yourself? TikToxic Effects of That-Girl Videos on Mood, Body Satisfaction, Dieting Intentions, and Self Discipline

Social Sciences
The “That Girl” self-optimization trend on TikTok, promoting beauty and productivity, had over 17.4 billion views by August 2024. “That Girl” video clips showcase perfectly organized daily routines, fitness activities, and healthy eating—allegedly to ...
Silvana Weber, Michelle Sadler, Christoph Mengelkamp   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The Impact of Chatbots on Adolescent Mental Health Development: A Comprehensive Literature Review

Journal of Multidisciplinary Healthcare
Yidong Wu,1,* Tong Wu,2,* Kerun Zhu,3 Xinyu Liu,3 Jiarui Liu,3 Yuyan Wang,3 Ruojin Shi,3 Jia Xiong,3 Xinyue Xing,3 Yao Lv,3 Yaohong Niu,3 Min Peng,4 Xingyan Du1 1School of Journalism and Communication, Lanzhou University, Lanzhou, 730000,
Wu Y, Wu T, Zhu K, Liu X, Liu J, Wang Y, Shi R, Xiong J, Xing X, Lv Y, Niu Y, Peng M, Du X   +12 more
doaj  

Towards a New Paradigm of Education; The End of Positional Hegemonies

Online Academic Journal of Information Technology, 2010
Teaching courses about New Media simultaneously in the various years of an undergraduate curriculum has interesting consequences. It happens every semester again and again, that you discover some new development in your field and begin to discuss it with
Emin Doğan Aydın
doaj   +1 more source