Results 91 to 100 of about 4,873,053 (351)

Administration of Long-Acting Injections [PDF]

open access: yes, 2018
Expanding the scope of pharmacy practice demonstrates that the profession has been successful at improving public health. Despite being a late adopter, New York\u27s limited experience with vaccines has improved immunization rates and lowered rates of ...
Noel, Christopher, Williams, Karl
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

How ‘smart’ is Public Administration in the Eyes of European Students? - Examining Behaviour Models in the Public Administration

open access: yesWroclaw Review of Law, Administration and Economics, 2020
Following study focussed on the perception of the public administration by the international students in the context of implementation of the concept of smart administration.
Stasz Marcin
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

STRATEGIC MANAGEMENT – MODEL AND TOOL FOR THE DEVELOPMENT OF THE LOCAL COMMUNITIES MANAGEMENT, IN THE STATE REFORM CONTEXT [PDF]

open access: yes
Ever since 2007, along with the completion of the EU accession process, but also before that, our country has constantly focused on improving local government standards either through a solid and sustained reform or through public system management ...
Ana Claudia TAPARDEL
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Cholic acid biosynthesis: conversion of 5β-cholestane-3α,7α,12α,25-tetrol into 5β-cholestane-3α,7α, 12α,24β,25-pentol by human and rat liver microsomes

open access: yesJournal of Lipid Research, 1977
This paper describes the conversion of 5β-cholestane-3α,7α,12α,25-tetrol into 5β-cholestane-3α,7α,12α,24β,25-pentol by liver microsomes. A sensitive radioactive assay for measuring the formation of 5β-cholestane-3α,7α,12α,24β,25-pentol was developed ...
F W Cheng   +6 more
doaj   +1 more source

STRUCTURAL DYNAMIC OF THE PUBLIC SECTOR AND MULTILEVEL GOVERNANCE: BETWEEN HIERARCHIES, MARKET AND NETWORK FORMS [PDF]

open access: yes
In the current economic, social and political context, the problem of the competitiveness reform in public sector lies in the assumption of strategic approaches focused on meeting the public interest, with the lowest cost for society.
Lumini?a Gabriela POPESCU
core  

Changes in the system of organization and financing of culture in Poland in the years 2001-2008 [PDF]

open access: yes, 2010
This article will show the major reforms and changes in public administration system in Poland according to changes in the sphere of culture in the years 2001-2009 and the final form of the culture finance system. The reason of this time horizon is, that
Suchecki, Adam Mateusz
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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