Results 91 to 100 of about 3,559,907 (314)

Politics, Relief, and Reform: The Transformation of America's Social Welfare System during the New Deal [PDF]

open access: yes
The American social welfare system was transformed during the 1930s. Prior to the New Deal public relief was administered almost exclusively by local governments. The administration of local public relief was widely thought to be corrupt.
John Joseph Wallis   +2 more
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

STRUCTURAL DYNAMIC OF THE PUBLIC SECTOR AND MULTILEVEL GOVERNANCE: BETWEEN HIERARCHIES, MARKET AND NETWORK FORMS [PDF]

open access: yes
In the current economic, social and political context, the problem of the competitiveness reform in public sector lies in the assumption of strategic approaches focused on meeting the public interest, with the lowest cost for society.
Lumini?a Gabriela POPESCU
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

NEW PUBLIC MANAGEMENT MODEL A SPECIAL ALTERNATIVE FOR THE ROMANIAN LOCAL PUBLIC ADMINISTRATION [PDF]

open access: yes
The paper is based on a special research started few years ago. The main objective of this research is to contribute to the innovation of the public management from the Romanian local public administration based on the best practices from the developed ...
Armenia ANDRONICEANU
core  

Sustainable development of regions: Creation of a future settlement by means of unification of territorial communities and implementation of innovative initiatives by agents of change [PDF]

open access: yes, 2019
Over the last 3-4 years, Ukraine has started and substantially advanced towards decentralization of public administration and has made a meaningful transformation of the local government system.
Akilina, Olena   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Evolution of public administration and its implication to management and business education

open access: yesJournal of Management and Business Education
The paper offers a thorough analysis of the historical development of public administration, aiming to gain deeper insights into the current challenges facing the discipline.
Arthur Kadakure, Michael Twum-Darko
doaj   +1 more source

Whither Public Interest: The Case of Greece's Public Finances [PDF]

open access: yes
During the last three decades there has been an almost continuous undermining of the public interest by private interests operating either outside or inside Greek public administration.
Christos Tsitsikas, Thomas Moutos
core  

Information and Communication Technology and Public Innovation: Assessing the ICT-driven Modernization of Public Administration [PDF]

open access: yes, 2006
The modernization of public administration is a recurring theme on the political and public agenda in many countries. Modernization presupposes innovation. However, is an innovative public administration a contradiction in terminis?
Bekkers, V.J.J.M. (Victor)   +2 more
core  

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